8VDE
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8VD4
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8VD5
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8V8B
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4AGO
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174 | 分子名称: | CELLULAR TUMOR ANTIGEN P53, TERT-BUTYL [3-(3-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-HYDROXY-5-IODOPHENYL)PROP-2-YN-1-YL]CARBAMATE, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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4AGN
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5116 | 分子名称: | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-(3-HYDROXYPROP-1-YN-1-YL)-6-IODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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4AGQ
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5196 | 分子名称: | 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-[3-(phenylamino)prop-1-yn-1-yl]phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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4AGP
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176 | 分子名称: | 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-(3-phenoxyprop-1-yn-1-yl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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4AGM
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086 | 分子名称: | 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4,6-DIIODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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4AGL
| Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan784 | 分子名称: | 2,4-BIS(IODANYL)-6-[[METHYL-(1-METHYLPIPERIDIN-4-YL)AMINO]METHYL]PHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R. | 登録日 | 2012-01-30 | 公開日 | 2012-03-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53. J.Am.Chem.Soc., 134, 2012
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6KYF
| Crystal structure of an anti-CRISPR protein | 分子名称: | AcrF11, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Niu, Y, Wang, H, Zhang, Y, Feng, Y. | 登録日 | 2019-09-18 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation. Mol.Cell, 80, 2020
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6O9N
| Structural insights on a new fungal aryl-alcohol oxidase | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kadowaki, M.A.S, Polikarpov, I. | 登録日 | 2019-03-14 | 公開日 | 2020-03-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | 主引用文献 | Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77. Biochim Biophys Acta Gen Subj, 1864, 2020
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6P1F
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6PFY
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6P17
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6P1E
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6P16
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6P1G
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6MH4
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6PGK
| Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I XFEL at 2.9 A | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Fromme, R, Gisriel, C, Fromme, P. | 登録日 | 2019-06-24 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Membrane protein megahertz crystallography at the European XFEL. Nat Commun, 10, 2019
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6MW8
| UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... | 著者 | Kim, H.W, Wood, Z.A, West, C.M. | 登録日 | 2018-10-29 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.756 Å) | 主引用文献 | A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii . J.Biol.Chem., 295, 2020
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6MJV
| A consensus human beta defensin | 分子名称: | Human beta-defensin | 著者 | Amero, C, Villegas-Moreno, J, Rodriguez, A, Norton, R.S, Corzo, G. | 登録日 | 2018-09-22 | 公開日 | 2019-08-28 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Antimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10. Proteins, 88, 2020
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6MW5
| UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Platinum | 分子名称: | 1,2-ETHANEDIOL, PLATINUM (II) ION, UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase, ... | 著者 | Kim, H.W, Wood, Z.A, West, C.M. | 登録日 | 2018-10-29 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii . J.Biol.Chem., 295, 2020
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6MH5
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3SA0
| Complex of ERK2 with norathyriol | 分子名称: | Mitogen-activated protein kinase 1, SULFATE ION, norathyriol | 著者 | Kurinov, I, Malakhova, M. | 登録日 | 2011-06-02 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5947 Å) | 主引用文献 | Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases. Cancer Res., 72, 2012
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