7LMA
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![BU of 7lma by Molmil](/molmil-images/mine/7lma) | Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | 著者 | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | 登録日 | 2021-02-05 | 公開日 | 2021-05-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
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3GNZ
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![BU of 3gnz by Molmil](/molmil-images/mine/3gnz) | Toxin fold for microbial attack and plant defense | 分子名称: | 25 kDa protein elicitor, MAGNESIUM ION | 著者 | Ottmann, C, Luberacki, B, Kuefner, I, Koch, W, Brunner, F, Weyand, M, Mattinen, L, Pirhonen, M, Anderluh, G, Seitz, H.U, Nuernberger, T, Oecking, C. | 登録日 | 2009-03-18 | 公開日 | 2009-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A common toxin fold mediates microbial attack and plant defense Proc.Natl.Acad.Sci.USA, 106, 2009
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2Y1Y
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![BU of 2y1y by Molmil](/molmil-images/mine/2y1y) | Human alphaB crystallin ACD(residues 71-157) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ALPHA-CRYSTALLIN B CHAIN, | 著者 | Naylor, C.E, Bagneris, C, Clark, A.R, Keep, N.H, Slingsby, C. | 登録日 | 2010-12-10 | 公開日 | 2011-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove J.Mol.Biol., 408, 2011
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2Y22
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![BU of 2y22 by Molmil](/molmil-images/mine/2y22) | Human AlphaB-crystallin Domain (residues 67-157) | 分子名称: | ALPHA-CRYSTALLIN B | 著者 | Naylor, C.E, Bagneris, C, Clark, A.R, Keep, N.H, Slingsby, C. | 登録日 | 2010-12-13 | 公開日 | 2011-03-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove J.Mol.Biol., 408, 2011
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2XYY
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![BU of 2xyy by Molmil](/molmil-images/mine/2xyy) | De Novo model of Bacteriophage P22 procapsid coat protein | 分子名称: | COAT PROTEIN | 著者 | Chen, D.-H, Baker, M.L, Hryc, C.F, DiMaio, F, Jakana, J, Wu, W, Dougherty, M, Haase-Pettingell, C, Schmid, M.F, Jiang, W, Baker, D, King, J.A, Chiu, W. | 登録日 | 2010-11-19 | 公開日 | 2011-02-02 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural Basis for Scaffolding-Mediated Assembly and Maturation of a DsDNA Virus. Proc.Natl.Acad.Sci.USA, 108, 2011
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1O9S
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![BU of 1o9s by Molmil](/molmil-images/mine/1o9s) | Crystal structure of a ternary complex of the human histone methyltransferase SET7/9 | 分子名称: | GENE FRAGMENT FOR HISTONE H3, HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, ... | 著者 | Xiao, B, Jing, C, Wilson, J.R, Walker, P.A, Vasisht, N, Kelly, G, Howell, S, Taylor, I.A, Blackburn, G.M, Gamblin, S.J. | 登録日 | 2002-12-18 | 公開日 | 2003-02-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9 Nature, 421, 2003
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4C4Z
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![BU of 4c4z by Molmil](/molmil-images/mine/4c4z) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 | 分子名称: | 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4Y
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![BU of 4c4y by Molmil](/molmil-images/mine/4c4y) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A4 | 分子名称: | 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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4C4X
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![BU of 4c4x by Molmil](/molmil-images/mine/4c4x) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9 | 分子名称: | 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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1QEW
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![BU of 1qew by Molmil](/molmil-images/mine/1qew) | HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) COMPLEX WITH A NONAMERIC PEPTIDE FROM MELANOMA-ASSOCIATED ANTIGEN 3 (RESIDUES 271-279) | 分子名称: | PROTEIN (BETA-2-MICROGLOBULIN), PROTEIN (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-35 B* 3501 ALPHA CHAIN), ... | 著者 | Orth, P, Alings, C, Saenger, W, Ziegler, A. | 登録日 | 1999-04-02 | 公開日 | 2003-11-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201)
COMPLEX WITH A NONAMERIC PEPTIDE FROM MELANOMA-ASSOCIATED
ANTIGEN 3 (RESIDUES 271-279) To be Published
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1SNT
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![BU of 1snt by Molmil](/molmil-images/mine/1snt) | Structure of the human cytosolic sialidase Neu2 | 分子名称: | Sialidase 2 | 著者 | Chavas, L.M.G, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Kato, R, Monti, E, Wakatsuki, S. | 登録日 | 2004-03-12 | 公開日 | 2004-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION J.Biol.Chem., 280, 2005
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1I0A
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3TE5
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![BU of 3te5 by Molmil](/molmil-images/mine/3te5) | structure of the regulatory fragment of sacchromyces cerevisiae ampk in complex with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Carbon catabolite-derepressing protein kinase, Nuclear protein SNF4, ... | 著者 | Mayer, F.V, Heath, R, Underwood, E, Sanders, M.J, Carmena, D, McCartney, R, Leiper, F.C, Xiao, B, Jing, C, Walker, P.A, Haire, L.F, Ogrodowicz, R, Martin, S.R, Schmidt, M.C, Gamblin, S.J, Carling, D. | 登録日 | 2011-08-12 | 公開日 | 2011-11-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. Cell Metab, 14, 2011
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7ATI
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![BU of 7ati by Molmil](/molmil-images/mine/7ati) | Crystal structure of dimeric chlorite dismutase variant Q74V (CCld Q74V) from Cyanothece sp. PCC7425 | 分子名称: | Chlorite dismutase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Schmidt, D, Mlynek, G, Djinovic-Carugo, K, Obinger, C. | 登録日 | 2020-10-30 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis. Biochemistry, 60, 2021
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7ASB
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![BU of 7asb by Molmil](/molmil-images/mine/7asb) | Crystal structure of dimeric chlorite dismutase variant Q74E (CCld Q74E) from Cyanothece sp. PCC7425 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chlorite dismutase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Schmidt, D, Mlynek, G, Djinovic-Carugo, K, Obinger, C. | 登録日 | 2020-10-27 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis. Biochemistry, 60, 2021
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2VIE
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![BU of 2vie by Molmil](/molmil-images/mine/2vie) | Human BACE-1 in complex with N-((1S,2R)-1-benzyl-2-hydroxy-3-((1,1,5- trimethylhexyl)amino)propyl)-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl) benzamide | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(1,1,5-trimethylhexyl)amino]propyl}-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | 著者 | Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G. | 登録日 | 2007-11-30 | 公開日 | 2008-01-29 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bace-1 Inhibitors Part 2: Identification of Hydroxy Ethylamines (Heas) with Reduced Peptidic Character. Bioorg.Med.Chem.Lett., 18, 2008
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2VJ7
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![BU of 2vj7 by Molmil](/molmil-images/mine/2vj7) | Human BACE-1 in complex with 3-(ethylamino)-N-((1S,2R)-2-hydroxy-1-(phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino)propyl)-5-(2-oxo-1-pyrrolidinyl)benzamide | 分子名称: | BETA-SECRETASE 1, N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | 著者 | Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G. | 登録日 | 2007-12-06 | 公開日 | 2008-01-29 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Bace-1 Inhibitors Part 2: Identification of Hydroxy Ethylamines (Heas) with Reduced Peptidic Character. Bioorg.Med.Chem.Lett., 18, 2008
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2VIX
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![BU of 2vix by Molmil](/molmil-images/mine/2vix) | Methylated Shigella flexneri MxiC | 分子名称: | ACETATE ION, GLYCEROL, PROTEIN MXIC | 著者 | Deane, J.E, Roversi, P, King, C, Johnson, S, Lea, S.M. | 登録日 | 2007-12-05 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structures of the Shigella Flexneri Type 3 Secretion System Protein Mxic Reveal Conformational Variability Amongst Homologues. J.Mol.Biol., 377, 2008
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2V9A
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![BU of 2v9a by Molmil](/molmil-images/mine/2v9a) | Structure of Citrate-free Periplasmic Domain of Sensor Histidine Kinase CitA | 分子名称: | SENSOR KINASE CITA | 著者 | Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S. | 登録日 | 2007-08-23 | 公開日 | 2008-03-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita. J.Mol.Biol., 377, 2008
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3F9P
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![BU of 3f9p by Molmil](/molmil-images/mine/3f9p) | Crystal structure of myeloperoxidase from human leukocytes | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | Carpena, X, Fita, I, Obinger, C. | 登録日 | 2008-11-14 | 公開日 | 2009-07-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases. J.Biol.Chem., 284, 2009
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1XA8
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![BU of 1xa8 by Molmil](/molmil-images/mine/1xa8) | Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa) | 分子名称: | GLUTATHIONE, GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, ... | 著者 | Neculai, A.M, Neculai, D, Griesinger, C, Vorholt, J.A, Becker, S. | 登録日 | 2004-08-25 | 公開日 | 2004-11-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A dynamic zinc redox switch J.Biol.Chem., 280, 2005
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2VJ6
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![BU of 2vj6 by Molmil](/molmil-images/mine/2vj6) | Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(ethylamino)-5-(2-oxo-1-pyrrolidinyl)benzamide | 分子名称: | BETA-SECRETASE 1, N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | 著者 | Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G. | 登録日 | 2007-12-06 | 公開日 | 2008-01-29 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Bace-1 Inhibitors Part 2: Identification of Hydroxy Ethylamines (Heas) with Reduced Peptidic Character. Bioorg.Med.Chem.Lett., 18, 2008
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2VIY
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![BU of 2viy by Molmil](/molmil-images/mine/2viy) | Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(pentylsulfonyl)benzamide | 分子名称: | BETA-SECRETASE 1, N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(pentylsulfonyl)benzamide | 著者 | Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G. | 登録日 | 2007-12-06 | 公開日 | 2008-01-29 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Bace-1 Inhibitors Part 1: Identification of Novel Hydroxy Ethylamines (Heas). Bioorg.Med.Chem.Lett., 18, 2008
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2WF1
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![BU of 2wf1 by Molmil](/molmil-images/mine/2wf1) | Human BACE-1 in complex with 7-ethyl-N-((1S,2R)-2-hydroxy-3-(((3-(methyloxy)phenyl(methyl)amino)-1-(phenylmethyl)propyl)-1-methyl-3,4- dihydro-1H-(1,2,5)thiadiazepino(3,4,5-hi)indole-9-carboxamide 2,2- dioxide | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-7-ethyl-1-methyl-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide 2,2-dioxide | 著者 | Charrier, N, Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Hubbard, J, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2009-04-02 | 公開日 | 2009-05-19 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Second Generation of Bace-1 Inhibitors Part 2: Optimisation of the Non-Prime Side Substituent. Bioorg.Med.Chem.Lett., 19, 2009
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2WF2
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![BU of 2wf2 by Molmil](/molmil-images/mine/2wf2) | Human BACE-1 in complex with 8-ethyl-N-((1S,2R)-2-hydroxy-3-(((3-(methyloxy)phenyl)methyl)amino)-1-(phenylmethyl)propyl)-1-methyl-3,4,7, 8-tetrahydro-1H,6H-(1,2,5)thiadiazepino(5,4,3-de)quinoxaline-10- carboxamide 2,2-dioxide | 分子名称: | BETA-SECRETASE 1, N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-8-ETHYL-1-METHYL-3,4,7,8-TETRAHYDRO-1H,6H-[1,2,5]THIADIAZEPINO[5,4,3-DE]QUINOXALINE-10-CARBOXAMIDE 2,2-DIOXIDE | 著者 | Charrier, N, Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Hubbard, J, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2009-04-02 | 公開日 | 2009-05-19 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Second Generation of Bace-1 Inhibitors Part 2: Optimisation of the Non-Prime Side Substituent. Bioorg.Med.Chem.Lett., 19, 2009
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