6KI2
 
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4DNW
 | | Crystal structure of UVB-resistance protein UVR8 | | 分子名称: | AT5g63860/MGI19_6 | | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Wang, J, Shi, Y. | | 登録日 | 2012-02-09 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.773 Å) | | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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6VIZ
 | | BRD4_Bromodomain1 complex with pyrrolopyridone compound 27 | | 分子名称: | 4-[2-(2,6-dimethylphenoxy)-5-(ethylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 4 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.391 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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6VIY
 | | BRD2_Bromodomain2 complex with pyrrolopyridone compound 27 | | 分子名称: | 4-[2-(2,6-dimethylphenoxy)-5-(ethylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 2 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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4DNU
 | | Crystal structure of the W285A mutant of UVB-resistance protein UVR8 | | 分子名称: | AT5g63860/MGI19_6 | | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y. | | 登録日 | 2012-02-09 | | 公開日 | 2012-03-07 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.764 Å) | | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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6VIX
 | | BRD4_Bromodomain2 complex with pyrrolopyridone compound 18 | | 分子名称: | 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 4 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.116 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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6VIW
 | | BRD4_Bromodomain1 complex with pyrrolopyridone compound 18 | | 分子名称: | 4-[2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl]-N-ethyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide, Bromodomain-containing protein 4 | | 著者 | Longenecker, K.L, Park, C.H, Qiu, W. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.429 Å) | | 主引用文献 | Discovery ofN-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J.Med.Chem., 63, 2020
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4DNV
 | | Crystal structure of the W285F mutant of UVB-resistance protein UVR8 | | 分子名称: | AT5g63860/MGI19_6 | | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y. | | 登録日 | 2012-02-09 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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4REY
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4WRS
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4XGY
 | | GFP based antibody (fluorobody) | | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Green fluorescent protein, mAb LCDR3 | | 著者 | Shi, N, Chen, Y.G, Wang, S.H. | | 登録日 | 2015-01-03 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.494 Å) | | 主引用文献 | The structure of a GFP-based antibody (fluorobody) to TLH, a toxin from Vibrio parahaemolyticus.
Acta Crystallogr.,Sect.F, 71, 2015
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5J8V
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5GHY
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4YRB
 | | mouse TDH mutant R180K with NAD+ bound | | 分子名称: | L-threonine 3-dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | He, C, Li, F. | | 登録日 | 2015-03-14 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
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5GHZ
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4YRA
 | | mouse TDH in the apo form | | 分子名称: | L-threonine 3-dehydrogenase, mitochondrial | | 著者 | He, C, Li, F. | | 登録日 | 2015-03-14 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
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4YR9
 | | mouse TDH with NAD+ bound | | 分子名称: | GLYCEROL, L-threonine 3-dehydrogenase, mitochondrial, ... | | 著者 | He, C, Li, F. | | 登録日 | 2015-03-14 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights on mouse l-threonine dehydrogenase: A regulatory role of Arg180 in catalysis
J.Struct.Biol., 192, 2015
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5GHX
 | | Crystal structure of beta-lactamase PenP mutant-E166H | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Beta-lactamase | | 著者 | Pan, X, Zhao, Y. | | 登録日 | 2016-06-21 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis
J. Biol. Chem., 292, 2017
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4JWR
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7TEI
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7TF8
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7THT
 | | CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ... | | 著者 | Manne, K, May, A, Acharya, P. | | 登録日 | 2022-01-12 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
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7TL9
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7TL1
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2PPH
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