8Y0F
 
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7UFH
 | | Integrin alpha IIB beta3 complex with fradafiban (Mn/Ca) | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-22 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.99768162 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UDH
 | | Integrin alpha IIB beta3 complex with BMS4-3 | | 分子名称: | (4-{[(5S)-3-(piperidin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-19 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.99998844 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UK9
 | | Integrin alpha IIB beta3 complex with lamifiban (Mn) | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-31 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.60001969 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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6JW4
 | | Degenerate RVD RG forms a distinct loop conformation | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5HC)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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7UCY
 | | Integrin alpha IIB beta3 complex with gantofiban | | 分子名称: | (4-{[(5R)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-17 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.34996319 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UKT
 | | Integrin alpha IIB beta3 complex with BMS4.2 | | 分子名称: | (1-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperidin-4-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-04-01 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.36994433 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7U9V
 | | Integrin alpha IIB beta3 complex with BMS4-1 | | 分子名称: | (4-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 light chain, ... | | 著者 | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-11 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.25492167 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UJK
 | | Integrin alpha IIB beta3 complex with lamifiban | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-30 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.43265581 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UKO
 | | Integrin alpha IIB beta3 complex with sibrafiban (Mn) | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-04-01 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UDG
 | | Integrin alpha IIB beta3 complex with lotrafiban | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-19 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.800069 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UE0
 | | Integrin alpha IIB beta3 complex with fradafiban | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-20 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.741962 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UKP
 | | Integrin alpha IIB beta3 complex with a gantofiban analog | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-04-01 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.80112982 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7U9F
 | | Integrin alpha IIB beta3 complex with BMS compound 4 in Mn2+ | | 分子名称: | (4-{[(5S)-3-{4-[(E)-imino(4-methylpiperazin-1-yl)methyl]phenyl}-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-10 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.70000529 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UBR
 | | Integrin alpha IIB beta3 complex with GR144053 | | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-15 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.04992747 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7UJE
 | | Integrin alpha IIB beta3 complex with UR2922 in Mn2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | | 登録日 | 2022-03-30 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.499968 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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2XWC
 | | Crystal structure of the DNA binding domain of human TP73 refined at 1.8 A resolution | | 分子名称: | GLYCEROL, TRIS(HYDROXYETHYL)AMINOMETHANE, TUMOUR PROTEIN P73, ... | | 著者 | Canning, P, Zhang, Y, Vollmar, M, Krojer, T, Ugochukwu, E, Muniz, J.R.C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | | 登録日 | 2010-11-03 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
J.Mol.Biol., 423, 2012
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7W3Y
 | | CryoEM structure of human Kv4.3 | | 分子名称: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3 | | 著者 | Ma, D.M, Guo, J.T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
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7W6S
 | | CryoEM structure of human KChIP2-Kv4.3 complex | | 分子名称: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2 | | 著者 | Ma, D.M, Guo, J.T. | | 登録日 | 2021-12-02 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
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7W6N
 | | CryoEM structure of human KChIP1-Kv4.3 complex | | 分子名称: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | | 著者 | Ma, D.M, Guo, J.T. | | 登録日 | 2021-12-02 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
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7W6T
 | | CryoEM structure of human KChIP1-Kv4.3-DPP6 complex | | 分子名称: | Dipeptidyl aminopeptidase-like protein 6, Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | | 著者 | Ma, D.M, Guo, J.T. | | 登録日 | 2021-12-02 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Cell Res., 32, 2022
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6JW5
 | | RVD Q* recognizes 5hmC through water-mediated H bonds | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5HC)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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6JW0
 | | Universal RVD R* accommodates cytosine via water-mediated interactions | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*CP*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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6JW3
 | | Degenerate RVD RG forms a distinct loop conformation | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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7W8S
 | | Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with American mink ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | | 著者 | Su, C, Qi, J.X, Gao, G.F. | | 登録日 | 2021-12-08 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants.
J.Virol., 96, 2022
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