381D
| BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES | 分子名称: | 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*TP*GP*(G49)P*CP*CP*G)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*G)-3') | 著者 | Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. | 登録日 | 1998-02-18 | 公開日 | 1998-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
|
|
2ZX6
| alpha-L-fucosidase complexed with inhibitor, F10-1C | 分子名称: | 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide, Alpha-L-fucosidase, putative | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2008-12-19 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
336D
| INTERACTION BETWEEN LEFT-HANDED Z-DNA AND POLYAMINE-3 THE CRYSTAL STRUCTURE OF THE D(CG)3 AND THERMOSPERMINE COMPLEX | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, N-(3-AMINO-PROPYL)-N-(5-AMINOPROPYL)-1,4-DIAMINOBUTANE | 著者 | Ohishi, H, Terasoma, N, Nakanishi, I, Van Der Marel, G, Van Boom, J.H, Rich, A, Wang, A.H.-J, Hakoshima, T, Tomita, K.-I. | 登録日 | 1997-06-24 | 公開日 | 1998-04-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Interaction between left-handed Z-DNA and polyamine - 3. The crystal structure of the d(CG)3 and thermospermine complex. FEBS Lett., 398, 1996
|
|
2Z7H
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-210 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, {1-HYDROXY-3-[METHYL(4-PHENYLBUTYL)AMINO]PROPANE-1,1-DIYL}BIS(PHOSPHONIC ACID) | 著者 | Cao, R, Chen, C.K.-M, Guo, R.-T, Hudock, M, Wang, A.H.-J, Oldfield, E. | 登録日 | 2007-08-23 | 公開日 | 2008-05-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins, 73, 2008
|
|
2ZXB
| alpha-L-fucosidase complexed with inhibitor, ph-6FNJ | 分子名称: | (2S,3R,4S,5R)-2-benzylpiperidine-3,4,5-triol, Alpha-L-fucosidase, putative | 著者 | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | 登録日 | 2008-12-22 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
380D
| BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES | 分子名称: | 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3') | 著者 | Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. | 登録日 | 1998-02-18 | 公開日 | 1998-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
|
|
3AMH
| crystal structure of cellulase 12A from Thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
|
|
3AMM
| Cellotetraose complex of cellulase 12A from thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
|
|
3AMN
| E134C-Cellobiose complex of cellulase 12A from thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
|
|
3C12
| |
3AMP
| E134C-Cellotetraose complex of cellulase 12A from thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
|
|
3AMQ
| E134C-Cellobiose co-crystal of cellulase 12A from thermotoga maritima | 分子名称: | Endo-1,4-beta-glucanase, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | 登録日 | 2010-08-20 | 公開日 | 2011-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
|
|
482D
| RELEASE OF THE CYANO MOIETY IN THE CRYSTAL STRUCTURE OF N-CYANOMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN COMPLEXED WITH D(CGATCG) | 分子名称: | 5'-D(*CP*GP*AP*TP*CP*G)-3', N-HYDROXYMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN | 著者 | Saminadin, P, Dautant, A, Mondon, M, Langlois D'Estaintot, B, Courseille, C, Precigoux, G. | 登録日 | 1999-07-27 | 公開日 | 1999-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG). Eur.J.Biochem., 267, 2000
|
|
7D1D
| Crystal structure of Bacteroides thetaiotaomicron glutaminyl cyclase bound to 1-benzylimidazole | 分子名称: | 1-BENZYL-1H-IMIDAZOLE, Glutamine cyclotransferase, ZINC ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-14 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D2B
| Crystal structure of Ixodes scapularis glutaminyl cyclase with a Ni ion bound to the active site | 分子名称: | Glutaminyl-peptide cyclotransferase, NICKEL (II) ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-16 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D2I
| Crystal structure of Ixodes scapularis glutaminyl cyclase with a Fe ion bound to the active site | 分子名称: | FE (III) ION, Glutaminyl-peptide cyclotransferase, SULFATE ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-16 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D23
| Crystal structure of Ixodes scapularis glutaminyl cyclase with one K ion bound to the active site | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutaminyl-peptide cyclotransferase, POTASSIUM ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-15 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1Y
| Crystal structure of Ixodes scapularis glutaminyl cyclase with two Co ions bound to the active site | 分子名称: | COBALT (II) ION, Glutaminyl-peptide cyclotransferase | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-15 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1P
| Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cd ions bound to the active site | 分子名称: | BICARBONATE ION, CADMIUM ION, Glutaminyl-peptide cyclotransferase | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-15 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D21
| Crystal structure of Ixodes scapularis glutaminyl cyclase with two Zn ions bound to the active site | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glutaminyl-peptide cyclotransferase, ZINC ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-15 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D17
| Crystal structure of Macrostomum lignano glutaminyl cyclase | 分子名称: | Glutaminyl-peptide cyclotransferase, ZINC ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-14 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1E
| Crystal structure of Bacteroides thetaiotaomicron glutaminyl cyclase bound to N-acetylhistamine | 分子名称: | Leucine aminopeptidase, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, ZINC ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-14 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1H
| Crystal structure of Ixodes scapularis glutaminyl cyclase with D238A mutation | 分子名称: | Glutaminyl-peptide cyclotransferase, ZINC ION | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-14 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1N
| Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cu ions bound to the active site | 分子名称: | BICARBONATE ION, COPPER (II) ION, Glutaminyl-peptide cyclotransferase | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-15 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|
7D1B
| Crystal structure of Fimbriiglobus ruber glutaminyl cyclase | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, CHLORIDE ION, GLYCEROL, ... | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | 登録日 | 2020-09-14 | 公開日 | 2021-04-14 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
|
|