7ENQ
| Crystal structure of human NAMPT in complex with compound NAT | 分子名称: | 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | 著者 | Wang, G, Wu, C, Liu, M, Yao, H, Li, C, Wang, L, Tang, Y. | 登録日 | 2021-04-19 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.204966 Å) | 主引用文献 | Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity. Cell Res., 32, 2022
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7DTR
| Structure of an AcrIF protein | 分子名称: | AcrIF24 | 著者 | Yue, F, Peipei, Y. | 登録日 | 2021-01-06 | 公開日 | 2022-01-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
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7XV6
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7XVA
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7XV9
| Crystal structure of the Human TR4 DNA-Binding Domain | 分子名称: | Nuclear receptor subfamily 2 group C member 2, ZINC ION | 著者 | Liu, Y, Chen, Z. | 登録日 | 2022-05-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
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7XV8
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7EKL
| Mitochondrial outer membrane protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION | 著者 | Zhang, S.S. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular insights into the human ABCB6 transporter. Cell Discov, 7, 2021
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7EKM
| Mitochondrial outer membrane protein | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial | 著者 | Zhang, S.S. | 登録日 | 2021-04-05 | 公開日 | 2021-08-25 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Molecular insights into the human ABCB6 transporter. Cell Discov, 7, 2021
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7FJM
| Cryo EM structure of lysosomal ATPase | 分子名称: | Polyamine-transporting ATPase 13A2 | 著者 | Zhang, S.S. | 登録日 | 2021-08-04 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2. Cell Discov, 7, 2021
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4L91
| Crystal structure of Human Hsp90 with X29 | 分子名称: | 4-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-6-chlorobenzene-1,3-diol, Heat shock protein HSP 90-alpha | 著者 | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | 登録日 | 2013-06-18 | 公開日 | 2014-06-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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4L94
| Crystal structure of Human Hsp90 with S46 | 分子名称: | (4-hydroxyphenyl)(4-methylpiperazin-1-yl)methanone, Heat shock protein HSP 90-alpha | 著者 | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | 登録日 | 2013-06-18 | 公開日 | 2014-06-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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4L8Z
| Crystal structure of Human Hsp90 with RL1 | 分子名称: | Heat shock protein HSP 90-alpha, [5-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl](3,4-dihydroisoquinolin-2(1H)-yl)methanone | 著者 | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | 登録日 | 2013-06-18 | 公開日 | 2014-06-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | 主引用文献 | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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7VG2
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7VG3
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7VXH
| Coxsackievirus B3 full particle at pH7.4 (VP3-234Q) | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Wang, Q.L, Liu, C.C. | 登録日 | 2021-11-12 | 公開日 | 2022-01-19 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VY0
| Coxsackievirus B3 full particle at pH7.4 (VP3-234N) | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Wang, Q.L, Liu, C.C. | 登録日 | 2021-11-13 | 公開日 | 2022-01-19 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VYM
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7VY5
| Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Wang, Q.L, Liu, C.C. | 登録日 | 2021-11-13 | 公開日 | 2022-01-19 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VY6
| Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Wang, Q.L, Liu, C.C. | 登録日 | 2021-11-13 | 公開日 | 2022-01-19 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VXZ
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7VYL
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7VYK
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7VXS
| Membrane arm of active state CI from Q10 dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-13 | 公開日 | 2022-11-23 | 最終更新日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7VYG
| Membrane arm of active state CI from rotenone dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-14 | 公開日 | 2022-11-23 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7VYF
| Matrix arm of active state CI from Rotenone dataset | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-14 | 公開日 | 2022-11-23 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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