6PJ3
 
 | | Crystal structure of the Klebsiella pneumoniae LpxH/JH-LPH-33 complex | | 分子名称: | 1,2-ETHANEDIOL, 1-[5-({4-[3-chloro-5-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one, MANGANESE (II) ION, ... | | 著者 | Cho, J, Zhou, P. | | 登録日 | 2019-06-27 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics.
Proc.Natl.Acad.Sci.USA, 117, 2020
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4MTT
 | | Ni- and Zn-bound GloA2 at low resolution | | 分子名称: | CHLORIDE ION, GLYCEROL, Lactoylglutathione lyase, ... | | 著者 | Bythell-Douglas, R, Bond, C.S. | | 登録日 | 2013-09-20 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity.
Chemistry, 21, 2015
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6I0N
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6I09
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6I0A
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7JMT
 | | Crystal structure of schistosome BCL-2 bound to ABT-737 | | 分子名称: | 4-{4-[(4'-CHLOROBIPHENYL-2-YL)METHYL]PIPERAZIN-1-YL}-N-{[4-({(1R)-3-(DIMETHYLAMINO)-1-[(PHENYLTHIO)METHYL]PROPYL}AMINO)-3-NITROPHENYL]SULFONYL}BENZAMIDE, BCL-2 protein | | 著者 | Smith, N.A, Smith, B.J, Lee, E.F, Colman, P.M, Fairlie, W.D. | | 登録日 | 2020-08-02 | | 公開日 | 2021-02-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2.
Acs Infect Dis., 7, 2021
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6I05
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3Q7V
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6C59
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6C8C
 | | Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06 | | 分子名称: | 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one, Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain | | 著者 | Najeeb, J, Zhou, P. | | 登録日 | 2018-01-24 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.
Cell, 178, 2019
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3Q81
 | | Imipenem acylated BlaR1 sensor domain from Staphylococcus aureus | | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase regulatory protein BlaR1, GLYCEROL | | 著者 | Borbulevych, O.Y, Mobashery, S, Baker, B.M. | | 登録日 | 2011-01-05 | | 公開日 | 2011-07-20 | | 最終更新日 | 2013-01-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
J.Biol.Chem., 286, 2011
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3Q7Z
 | | CBAP-acylated BlaR1 sensor domain from Staphylococcus aureus | | 分子名称: | (2R,4S)-2-[(1R)-1-{[(2'-carboxybiphenyl-2-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase regulatory protein BlaR1 | | 著者 | Borbulevych, O.Y, Mobashery, S, Baker, B.M. | | 登録日 | 2011-01-05 | | 公開日 | 2011-07-06 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
J.Biol.Chem., 286, 2011
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3Q82
 | | Meropenem acylated BlaR1 sensor domain from Staphylococcus aureus | | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase regulatory protein BlaR1, GLYCEROL | | 著者 | Borbulevych, O.Y, Mobashery, S, Baker, B.M. | | 登録日 | 2011-01-05 | | 公開日 | 2011-07-20 | | 最終更新日 | 2013-01-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
J.Biol.Chem., 286, 2011
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7LAM
 | | Crystal structure of Campylobacter jejuni Cj0843c lytic transglycosylase in complex with N,N',N''-triacetylchitotriose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CITRIC ACID, ... | | 著者 | van den Akker, F, Kumar, V. | | 登録日 | 2021-01-06 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of Campylobacter jejuni .
Biochemistry, 60, 2021
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7LAQ
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5Y2T
 | | Structure of PPARgamma ligand binding domain - lobeglitazone complex | | 分子名称: | (5S)-5-[[4-[2-[[6-(4-methoxyphenoxy)pyrimidin-4-yl]-methyl-amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | | 著者 | Im, Y.J, Lee, M. | | 登録日 | 2017-07-27 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of PPAR gamma complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs
Sci Rep, 7, 2017
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5Y2O
 | | Structure of PPARgamma ligand binding domain-pioglitazone complex | | 分子名称: | (5S)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | | 著者 | Im, Y.J, Lee, M. | | 登録日 | 2017-07-26 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structures of PPAR gamma complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs
Sci Rep, 7, 2017
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3IFN
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex | | 分子名称: | 12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein | | 著者 | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | 登録日 | 2009-07-24 | | 公開日 | 2009-11-17 | | 最終更新日 | 2013-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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3IFO
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-7:10D5) complex | | 分子名称: | 10D5 FAB antibody heavy chain, 10D5 FAB antibody light chain, Amyloid beta A4 protein | | 著者 | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | 登録日 | 2009-07-24 | | 公開日 | 2009-11-17 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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3IFP
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex | | 分子名称: | 12B4 FAB antibody heavy chain, 12B4 FAB antibody light chain, Amyloid beta A4 protein | | 著者 | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | 登録日 | 2009-07-24 | | 公開日 | 2009-11-17 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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3IFL
 | | X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12A11) complex | | 分子名称: | 12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein | | 著者 | Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. | | 登録日 | 2009-07-24 | | 公開日 | 2009-11-17 | | 最終更新日 | 2013-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease.
J.Biol.Chem., 285, 2010
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3KM5
 | | Crystal Structure Analysis of the K2 Cleaved Adhesin Domain of Lys-gingipain (Kgp) | | 分子名称: | CALCIUM ION, GLYCEROL, Lysine specific cysteine protease, ... | | 著者 | Li, N, Collyer, C.A, Hunter, N. | | 登録日 | 2009-11-09 | | 公開日 | 2010-03-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis
Mol.Microbiol., 76, 2010
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5AA4
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5A5X
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5AA2
 | | Crystal structure of MltF from Pseudomonas aeruginosa in complex with NAM-pentapeptide. | | 分子名称: | CHLORIDE ION, MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F, N-ACETYLGLUCOSAMINE-1,6-ANHYDRO-N-ACETYLMURAMIC ACID L-ALA-D-GLU-M-DAP-D-ALA-D-ALA | | 著者 | Dominguez-Gil, T, Acebron, I, Hermoso, J.A. | | 登録日 | 2015-07-23 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.
Structure, 24, 2016
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