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2N4X
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Structure of the Transmembrane Electron Transporter CcdA
分子名称: Cytochrome C-type biogenesis protein (CcdA)
著者Chou, J.J, Williamson, J.A.
登録日2015-07-01
公開日2016-05-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and multistate function of the transmembrane electron transporter CcdA.
Nat.Struct.Mol.Biol., 22, 2015
2N77
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NMR solution structure of a complex of PEP-19 bound to the C-domain of apo calmodulin
分子名称: Calmodulin, Purkinje cell protein 4
著者Wang, X, Putkey, J.A.
登録日2015-09-04
公開日2016-11-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献PEP-19 modulates calcium binding to calmodulin by electrostatic steering.
Nat Commun, 7, 2016
2NQJ
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Crystal structure of Escherichia coli endonuclease IV (Endo IV) E261Q mutant bound to damaged DNA
分子名称: 5'-D(*CP*GP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*(3DR)P*CP*GP*AP*CP*GP*AP*CP*G)-3', Endonuclease 4, ...
著者Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A.
登録日2006-10-31
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.
Nat.Struct.Mol.Biol., 15, 2008
2NQ9
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High resolution crystal structure of Escherichia coli endonuclease IV (Endo IV) Y72A mutant bound to damaged DNA
分子名称: 5'-D(*AP*TP*AP*TP*CP*T)-3', 5'-D(*AP*TP*CP*TP*GP*AP*AP*GP*TP*AP*T)-3', 5'-D(P*(3DR)P*AP*GP*AP*T)-3', ...
著者Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A.
登録日2006-10-30
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.
Nat.Struct.Mol.Biol., 15, 2008
2QQQ
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Crystal Structure of Novel Immune-Type Receptor 11 Extracellular Fragment from Ictalurus punctatus
分子名称: Novel immune-type receptor 11
著者Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W.
登録日2007-07-26
公開日2008-06-10
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition.
Immunity, 29, 2008
2QTE
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Crystal Structure of Novel Immune-Type Receptor 11 Extracellular Fragment Mutant N30D
分子名称: Novel immune-type receptor 11
著者Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W.
登録日2007-08-01
公開日2008-09-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition.
Immunity, 29, 2008
2QX4
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Crystal Structure of Quinone Reductase II
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
著者Calamini, B, Santarsiero, B.D, Boutin, J.A, Mesecar, A.D.
登録日2007-08-10
公開日2008-09-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2QJD
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Crystal Structure of Novel Immune-Type Receptor 10 Extracellular Fragment Mutant N30D
分子名称: Novel immune-type receptor 10
著者Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W.
登録日2007-07-06
公開日2008-06-17
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition.
Immunity, 29, 2008
2QP2
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Structure of a MACPF/perforin-like protein
分子名称: CALCIUM ION, Unknown protein
著者Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C.
登録日2007-07-22
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2QZ2
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Crystal structure of a glycoside hydrolase family 11 xylanase from Aspergillus niger in complex with xylopentaose
分子名称: Endo-1,4-beta-xylanase I, SODIUM ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ...
著者Vandermarliere, E, Rombouts, S, Strelkov, S.V, Delcour, J.A, Courtin, C.M, Rabijns, A.
登録日2007-08-16
公開日2007-12-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analysis shows substrate binding at the -3 to +1 active-site subsites and at the surface of glycoside hydrolase family 11 endo-1,4-beta-xylanases.
Biochem.J., 410, 2008
2QJM
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BU of 2qjm by Molmil
Crystal structure of the K271E mutant of Mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and D-mannonate
分子名称: D-MANNONIC ACID, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme
著者Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Vick, J.E, Gerlt, J.A, Almo, S.C.
登録日2007-07-08
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry, 46, 2007
2QTU
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BU of 2qtu by Molmil
Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand
分子名称: (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol, Estrogen receptor beta
著者Richardson, T.I, Dodge, J.A, Wang, Y, Durbin, J.D, Krishnan, V, Norman, B.H.
登録日2007-08-02
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.
Bioorg.Med.Chem.Lett., 17, 2007
2QX8
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Crystal Structure of Quinone Reductase II
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Calamini, B, Santarsiero, B.D, Boutin, J.A, Mesecar, A.D.
登録日2007-08-10
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
7JN1
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BU of 7jn1 by Molmil
Sheep Connexin-46 at 2.5 angstroms resolution, Lipid Class 3
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-3 protein
著者Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
登録日2020-08-03
公開日2020-09-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
7JMC
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Sheep Connexin-50 at 2.5 angstroms resolution, Lipid Class 3
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Gap junction alpha-8 protein
著者Flores, J.A, Haddad, B.G, Dolan, K.D, Myers, J.B, Yoshioka, C.C, Copperman, J, Zuckerman, D.M, Reichow, S.L.
登録日2020-07-31
公開日2020-09-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 angstrom.
Nat Commun, 11, 2020
3S9K
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Crystal structure of the Itk SH2 domain.
分子名称: CITRIC ACID, Tyrosine-protein kinase ITK/TSK
著者Joseph, R.E, Ginder, N.D, Hoy, J.A, Nix, J.C, Fulton, B.D, Honzatko, R.B, Andreotti, A.H.
登録日2011-06-01
公開日2012-02-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.F, 68, 2012
3RW9
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Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine
分子名称: 5'-S-(3-aminopropyl)-5'-thioadenosine, Spermidine synthase
著者Seckute, J, McCloskey, D.E, Thomas, H.J, Secrist III, J.A, Pegg, A.E, Ealick, S.E.
登録日2011-05-08
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
Protein Sci., 20, 2011
3UAG
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BU of 3uag by Molmil
UDP-N-ACETYLMURAMOYL-L-ALANINE:D-GLUTAMATE LIGASE
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
著者Bertrand, J.A, Auger, G, Martin, L, Fanchon, E, Blanot, D, Le Beller, D, Van Heijenoort, J, Dideberg, O.
登録日1999-02-24
公開日2000-02-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Determination of the MurD mechanism through crystallographic analysis of enzyme complexes.
J.Mol.Biol., 289, 1999
4MH7
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BU of 4mh7 by Molmil
Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1896
分子名称: CHLORIDE ION, MAGNESIUM ION, N-butyl-2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-methylpyrimidine-5-carboxamide, ...
著者Zhang, W, McIver, A, Stashko, M.A, Deryckere, D, Branchford, B.R, Hunter, D, Kireev, D.B, Miley, M.J, Norris-Drouin, J, Stewart, W.M, Lee, M, Sather, S, Zhou, Y, DiPaola, J.A, Machius, M, Janzen, W.P, Earp, H.S, Graham, D.K, Frye, S, Wang, X.
登録日2013-08-29
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis.
J.Med.Chem., 56, 2013
6TW5
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Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917
分子名称: 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Brannigan, J.A.
登録日2020-01-12
公開日2021-07-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917
To Be Published
6TW6
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Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-923
分子名称: 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Brannigan, J.A.
登録日2020-01-12
公開日2021-07-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-923
To Be Published
6TW7
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Leishmania major N-myristoyltransferase in complex with indazole inhibitor IMP-918
分子名称: Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, TETRADECANOYL-COA, ...
著者Brannigan, J.A.
登録日2020-01-12
公開日2021-07-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Leishmania major N-myristoyltransferase in complex with indazole inhibitor IMP-918
To Be Published
6TW8
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Leishmania major N-myristoyltransferase in complex with indazole inhibitor IMP-917
分子名称: 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ...
著者Brannigan, J.A.
登録日2020-01-12
公開日2021-07-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Leishmania major N-myristoyltransferase in complex with indazole inhibitor IMP-917
To Be Published
6UY5
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E. coli cysteine desulfurase SufS with a spontaneously rotated beta-hairpin
分子名称: Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE
著者Dunkle, J.A, Frantom, P.A.
登録日2019-11-11
公開日2020-03-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases
Acta Crystallogr.,Sect.D, 76, 2020
1NHC
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Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者van Pouderoyen, G, Snijder, H.J, Benen, J.A, Dijkstra, B.W.
登録日2002-12-19
公開日2003-11-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger.
Febs Lett., 554, 2003

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