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5DD6
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BU of 5dd6 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.mut58 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.mut58 FAB LIGHT CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
6CTE
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BU of 6cte by Molmil
77Se-NMR probes the protein environment of selenomethionine
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
著者Chen, Q, Rozovsky, S.
登録日2018-03-22
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
6CNE
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BU of 6cne by Molmil
Selenomethionine variant (V29SeM) of protein GB1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G, PHOSPHATE ION
著者Chen, Q.
登録日2018-03-08
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
6CPZ
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BU of 6cpz by Molmil
Selenomethionine mutant (I6Sem) of protein GB1 examined by X-ray diffraction
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G, ...
著者Chen, Q, Rozovsky, S.
登録日2018-03-14
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
4JSO
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BU of 4jso by Molmil
The X-ray crystal structure of a thermophilic cellobiose binding protein bound with laminaripentaose
分子名称: CALCIUM ION, Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, ...
著者Munshi, P, Cuneo, M.J.
登録日2013-03-22
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Molecular details of ligand selectivity determinants in a promiscuous beta-glucan periplasmic binding protein.
Bmc Struct.Biol., 13, 2013
6CHE
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BU of 6che by Molmil
Selenomethionine mutant (A34Sem) of protein GB1 examined by X-ray diffraction
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, IMIDAZOLE, Immunoglobulin G-binding protein G
著者Chen, Q.
登録日2018-02-22
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
6C9O
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BU of 6c9o by Molmil
Selenomethionine mutant (V29Sem) of protein GB1 examined by X-ray diffraction
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G
著者Chen, Q.
登録日2018-01-28
公開日2019-07-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 2020
4JSD
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BU of 4jsd by Molmil
The X-ray crystal structure of a thermophilic cellobiose binding protein bound with laminaribiose
分子名称: CALCIUM ION, Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, ...
著者Munshi, P, Cuneo, M.J.
登録日2013-03-22
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular details of ligand selectivity determinants in a promiscuous beta-glucan periplasmic binding protein.
Bmc Struct.Biol., 13, 2013
5DD3
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BU of 5dd3 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD0
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BU of 5dd0 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
著者Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
4IRV
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BU of 4irv by Molmil
Structure of the Helicobacter pylori CagA Oncogene Bound to the Human Tumor Suppressor Apoptosis-stimulating Protein of p53-2
分子名称: Apoptosis-stimulating of p53 protein 2, Cytotoxicity-associated immunodominant antigen
著者Stebbins, C.E, Nesic, D.
登録日2013-01-15
公開日2014-01-15
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
Proc.Natl.Acad.Sci.USA, 111, 2014
8DTK
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BU of 8dtk by Molmil
Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
著者May, A.J, Manne, K, Acharya, P.
登録日2022-07-25
公開日2023-08-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Biorxiv, 2023
7CH1
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BU of 7ch1 by Molmil
The overall structure of SLC26A9
分子名称: CHLORIDE ION, SODIUM ION, Solute carrier family 26 member 9
著者Chi, X.M, Chen, Y, Li, X.R, Zhang, Y.Y, Zhou, Q.
登録日2020-07-03
公開日2020-08-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence.
Cell Discov, 6, 2020
5X5O
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BU of 5x5o by Molmil
Crystal structure of ZAK in complex with compound D2829
分子名称: Mitogen-activated protein kinase kinase kinase MLT, N-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide
著者Dai, Y.B, Zhao, P, Yun, C.H.
登録日2017-02-17
公開日2017-12-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-alpha Motif Kinase (ZAK) Inhibitors.
J. Med. Chem., 60, 2017
7CWL
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BU of 7cwl by Molmil
SARS-CoV-2 spike protein and P17 fab complex with one RBD in close state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab P17 heavy chain, Fab P17 light chain, ...
著者Wang, X, Wang, N.
登録日2020-08-29
公開日2021-01-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWM
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BU of 7cwm by Molmil
Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P17 heavy chain, ...
著者Wang, N, Wang, X.
登録日2020-08-29
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7DTZ
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BU of 7dtz by Molmil
FGFR4 complex with a covalent inhibitor
分子名称: Fibroblast growth factor receptor 4, N-[2-[[5-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]methoxy]pyrimidin-2-yl]amino]-3-methyl-phenyl]-2-fluoranyl-prop-2-enamide, SULFATE ION
著者Chen, X.J, Dai, S.Y, Chen, Y.H.
登録日2021-01-07
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7WH9
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BU of 7wh9 by Molmil
holo structure of emodin 1-OH O-methyltransferase complex with emodin and S-Adenosyl-L-homocysteine
分子名称: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, O-methyltransferase gedA, S-ADENOSYL-L-HOMOCYSTEINE
著者Liang, Y.J, Lu, X.F, Qi, F.F, Xue, Y.Y.
登録日2021-12-30
公開日2023-01-11
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Characterization and Structural Analysis of Emodin- O -Methyltransferase from Aspergillus terreus.
J.Agric.Food Chem., 70, 2022
7CWN
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BU of 7cwn by Molmil
P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, N, Wang, X.
登録日2020-08-29
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWO
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BU of 7cwo by Molmil
SARS-CoV-2 spike protein RBD and P17 fab complex
分子名称: Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab
著者Wang, X, Wang, N.
登録日2020-08-29
公開日2020-12-16
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7DHY
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BU of 7dhy by Molmil
Arsenic-bound p53 DNA-binding domain mutant G245S
分子名称: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
著者Chen, S, Lu, M.
登録日2020-11-18
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
7DHZ
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BU of 7dhz by Molmil
Arsenic-bound p53 DNA-binding domain mutant R249S
分子名称: ARSENIC, Cellular tumor antigen p53, GLYCEROL, ...
著者Chen, S, Lu, M.
登録日2020-11-18
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site.
Cancer Cell, 39, 2021
7DSC
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BU of 7dsc by Molmil
CALHM1 open state with disordered CTH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
著者Ren, Y, Yang, X, Shen, Y.Q.
登録日2020-12-30
公開日2022-01-05
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022
7DSD
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BU of 7dsd by Molmil
CALHM1 close state with disordered CTH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
著者Ren, Y, Yang, X, Shen, Y.Q.
登録日2020-12-30
公開日2022-01-05
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022
7DSE
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BU of 7dse by Molmil
CALHM1 close state with ordered CTH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1
著者Ren, Y, Yang, X, Shen, Y.Q.
登録日2020-12-30
公開日2022-01-05
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel.
J.Biol.Chem., 298, 2022

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