7JKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jky by Molmil](/molmil-images/mine/7jky) | Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-126 | 分子名称: | Bromodomain-containing protein 4, N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide, SODIUM ION | 著者 | Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R. | 登録日 | 2020-07-29 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
|
|
7JKW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jkw by Molmil](/molmil-images/mine/7jkw) | Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with ZN1-99 | 分子名称: | Bromodomain-containing protein 4, N-(6-{5-[(azetidin-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridin-3-yl}-1-[1,1-di(pyridin-2-yl)ethyl]-1H-indol-4-yl)ethanesulfonamide | 著者 | Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R. | 登録日 | 2020-07-29 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
|
|
3HSZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hsz by Molmil](/molmil-images/mine/3hsz) | Crystal structure of E. coli HPPK(F123A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
|
|
3HT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ht0 by Molmil](/molmil-images/mine/3ht0) | Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP | 分子名称: | CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, HPPK, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
|
|
3HSG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hsg by Molmil](/molmil-images/mine/3hsg) | Crystal structure of E. coli HPPK(Y53A) in complex with MgAMPCPP | 分子名称: | ACETATE ION, CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-10 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
|
|
3HSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hsd by Molmil](/molmil-images/mine/3hsd) | Crystal structure of E. coli HPPK(Y53A) | 分子名称: | CHLORIDE ION, GLYCEROL, HPPK, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-10 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK. To be Published
|
|
3HSJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hsj by Molmil](/molmil-images/mine/3hsj) | Crystal structure of E. coli HPPK(N55A) | 分子名称: | ACETATE ION, GLYCEROL, HPPK | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-10 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
|
|
3QUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3quz by Molmil](/molmil-images/mine/3quz) | Structure of the mouse CD1d-NU-alpha-GalCer-iNKT TCR complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | 登録日 | 2011-02-24 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
|
|
3QUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3quy by Molmil](/molmil-images/mine/3quy) | Structure of the mouse CD1d-BnNH-GSL-1'-iNKT TCR complex | 分子名称: | (2S,3R,4S,5R,6S)-6-[(2S,3S,4R)-2-(hexacosanoylamino)-3,4-dihydroxy-octadecoxy]-3,4,5-trihydroxy-N-(phenylmethyl)oxane-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | 登録日 | 2011-02-24 | 公開日 | 2011-06-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
|
|
3QUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qux by Molmil](/molmil-images/mine/3qux) | Structure of the mouse CD1d-alpha-C-GalCer-iNKT TCR complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Li, Y, Girardi, E, Yu, E.D, Zajonc, D.M. | 登録日 | 2011-02-24 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis. Embo J., 30, 2011
|
|
3ILL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ill by Molmil](/molmil-images/mine/3ill) | |
3ILI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ili by Molmil](/molmil-images/mine/3ili) | Crystal structure of E. coli HPPK(D95A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-08-07 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
|
|
3ILO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ilo by Molmil](/molmil-images/mine/3ilo) | Crystal structure of E. coli HPPK(D97A) in complex with MgAMPCPP and 6-hydroxymethyl-7,8-dihydropterin | 分子名称: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-08-07 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
|
|
3ILJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ilj by Molmil](/molmil-images/mine/3ilj) | Crystal structure of E. coli HPPK(D95A) in complex with MgAMPCPP | 分子名称: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-08-07 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
|
|
2L93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l93 by Molmil](/molmil-images/mine/2l93) | |
2L92
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l92 by Molmil](/molmil-images/mine/2l92) | |
5Y2G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y2g by Molmil](/molmil-images/mine/5y2g) | Structure of MBP tagged GBS CAMP | 分子名称: | Maltose-binding periplasmic protein,Protein B, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Jin, T, Li, Y. | 登録日 | 2017-07-25 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure determination of the CAMP factor of Streptococcus agalactiae with the aid of an MBP tag and insights into membrane-surface attachment. Acta Crystallogr D Struct Biol, 75, 2019
|
|
2KNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kng by Molmil](/molmil-images/mine/2kng) | Solution structure of C-domain of Lsr2 | 分子名称: | Protein lsr2 | 著者 | Li, Y, Xia, B. | 登録日 | 2009-08-22 | 公開日 | 2010-03-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis Proc.Natl.Acad.Sci.USA, 2010
|
|
3KUE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kue by Molmil](/molmil-images/mine/3kue) | |
3KUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kug by Molmil](/molmil-images/mine/3kug) | |
3KUH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kuh by Molmil](/molmil-images/mine/3kuh) | Crystal structure of E. coli HPPK(H115A) in complex with AMPCPP and HP | 分子名称: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-11-27 | 公開日 | 2010-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Roles of residues E77 and H115 in E. coli HPPK To be Published
|
|
6L5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l5z by Molmil](/molmil-images/mine/6l5z) | |
5V4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v4b by Molmil](/molmil-images/mine/5v4b) | Crystal structure of the Skp1-FBXW7-DISC1 complex | 分子名称: | DISC1 peptide, F-box/WD repeat-containing protein 7, IMIDAZOLE, ... | 著者 | Li, Y, Baillie, G.S, Hao, B. | 登録日 | 2017-03-08 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Mol. Psychiatry, 23, 2018
|
|
3S4S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s4s by Molmil](/molmil-images/mine/3s4s) | Crystal structure of CD4 mutant bound to HLA-DR1 | 分子名称: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Li, Y. | 登録日 | 2011-05-20 | 公開日 | 2011-09-21 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
8XAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xab by Molmil](/molmil-images/mine/8xab) | |