2HS6
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2HS8
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1STC
| CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE | 分子名称: | CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE | 著者 | Prade, L, Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | 登録日 | 1997-10-10 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure, 5, 1997
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1WXE
| E.coli NAD Synthetase, AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1WXF
| E.coli NAD Synthetase | 分子名称: | NH(3)-dependent NAD(+) synthetase | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1C9T
| COMPLEX OF BDELLASTASIN WITH BOVINE TRYPSIN | 分子名称: | BDELLASTASIN, TRYPSIN | 著者 | Rester, U, Bode, W, Moser, M, Parry, M.A, Huber, R, Auerswald, E. | 登録日 | 1999-08-03 | 公開日 | 2000-08-03 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system. J.Mol.Biol., 293, 1999
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1VEB
| Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 5 | 分子名称: | (3R,4R)-N-{4-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-BENZYLOXY]-AZEPAN-3-YL}-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.-G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-03-29 | 公開日 | 2005-03-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
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2GSR
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1EJA
| STRUCTURE OF PORCINE TRYPSIN COMPLEXED WITH BDELLASTASIN, AN ANTISTASIN-TYPE INHIBITOR | 分子名称: | BDELLASTASIN, SODIUM ION, TRYPSIN | 著者 | Rester, U, Moser, M, Huber, R, Bode, W. | 登録日 | 2000-03-02 | 公開日 | 2001-03-02 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin. Acta Crystallogr.,Sect.D, 56, 2000
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1IXP
| Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-Phosphate synthase | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1IXO
| Enzyme-analogue substrate complex of Pyridoxine 5'-Phosphate Synthase | 分子名称: | Pyridoxine 5'-Phosphate synthase, SN-GLYCEROL-3-PHOSPHATE | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1Z1W
| Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-07 | 公開日 | 2005-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 394, 2005
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1IXN
| Enzyme-Substrate Complex of Pyridoxine 5'-Phosphate Synthase | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Pyridoxine 5'-Phosphate Synthase, SN-GLYCEROL-3-PHOSPHATE | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1Z5H
| Crystal structures of the Tricorn interacting Factor F3 from Thermoplasma acidophilum | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-18 | 公開日 | 2005-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 349, 2005
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3AZU
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1BVN
| PIG PANCREATIC ALPHA-AMYLASE IN COMPLEX WITH THE PROTEINACEOUS INHIBITOR TENDAMISTAT | 分子名称: | CALCIUM ION, CHLORIDE ION, PROTEIN (ALPHA-AMYLASE), ... | 著者 | Machius, M, Wiegand, G, Epp, O, Huber, R. | 登録日 | 1998-09-16 | 公開日 | 1998-09-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of porcine pancreatic alpha-amylase in complex with the microbial inhibitor Tendamistat. J.Mol.Biol., 247, 1995
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1N5W
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Oxidized form | 分子名称: | CU(I)-S-MO(VI)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-07 | 公開日 | 2002-12-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N63
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Carbon monoxide reduced state | 分子名称: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N61
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Dithionite reduced state | 分子名称: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N62
| Crystal Structure of the Mo,Cu-CO Dehydrogenase (CODH), n-butylisocyanide-bound state | 分子名称: | CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N60
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Cyanide-inactivated Form | 分子名称: | Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, Carbon monoxide dehydrogenase small chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1TLE
| LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES | 分子名称: | LAMININ | 著者 | Baumgartner, R, Czisch, M, Mayer, U, Schl, E.P, Huber, R, Timpl, R, Holak, T.A. | 登録日 | 1996-01-26 | 公開日 | 1997-02-12 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the nidogen binding LE module of the laminin gamma1 chain in solution. J.Mol.Biol., 257, 1996
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1JC9
| TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, techylectin-5A | 著者 | Kairies, N, Beisel, H.-G, Fuentes-Prior, P, Tsuda, R, Muta, T, Iwanaga, S, Bode, W, Huber, R, Kawabata, S. | 登録日 | 2001-06-08 | 公開日 | 2001-11-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems. Proc.Natl.Acad.Sci.USA, 98, 2001
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1XH7
| Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | 分子名称: | N-[4-({4-[5-(3,3-DIMETHYLPIPERIDIN-1-YL)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-09-17 | 公開日 | 2005-09-17 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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1XH9
| Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | 分子名称: | (R,R)-2,3-BUTANEDIOL, N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, ... | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-09-17 | 公開日 | 2005-09-17 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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