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6UTW
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BU of 6utw by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal)
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.854 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UUC
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BU of 6uuc by Molmil
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.096 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UU5
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BU of 6uu5 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes)
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.403 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6VPR
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BU of 6vpr by Molmil
Crystal structure of the C-terminal domain of DENR
Descriptor: ACETATE ION, Density-regulated protein, L(+)-TARTARIC ACID, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2020-02-04
Release date:2020-04-08
Last modified:2020-04-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the C-terminal domain of DENR.
Comput Struct Biotechnol J, 18, 2020
6UU2
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BU of 6uu2 by Molmil
E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.404 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UTX
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BU of 6utx by Molmil
E. coli sigma-S transcription initiation complex with an empty bubble ("Old" crystal)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6UUB
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BU of 6uub by Molmil
E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.955 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6VPQ
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BU of 6vpq by Molmil
Crystal structure of the C-terminal domain of DENR
Descriptor: ACETATE ION, CALCIUM ION, Density-regulated protein, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2020-02-04
Release date:2020-04-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the C-terminal domain of DENR.
Comput Struct Biotechnol J, 18, 2020
1VQ8
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BU of 1vq8 by Molmil
The structure of CCDA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQK
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BU of 1vqk by Molmil
The structure of CCDA-PHE-CAP-BIO bound to the a site of the ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQM
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BU of 1vqm by Molmil
The structure of the transition state analogue "DAN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQ9
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BU of 1vq9 by Molmil
The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VY5
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BU of 1vy5 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the post-catalysis state of peptide bond formation containing dipeptydil-tRNA in the A site and deacylated tRNA in the P site.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VY7
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BU of 1vy7 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Cytidine-Puromycin in the A site and acylated tRNA in the P site.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VQ4
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BU of 1vq4 by Molmil
The structure of the transition state analogue "DAA" bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQO
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BU of 1vqo by Molmil
The structure of CCPMN bound to the large ribosomal subunit haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VY6
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BU of 1vy6 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VQL
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BU of 1vql by Molmil
The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VY4
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BU of 1vy4 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing acylated tRNA-substrates in the A and P sites.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Steitz, T.A, Innis, C.A.
Deposit date:2014-05-13
Release date:2014-08-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Nat.Struct.Mol.Biol., 21, 2014
1VQ5
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BU of 1vq5 by Molmil
The structure of the transition state analogue "RAA" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQP
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BU of 1vqp by Molmil
The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1KFD
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BU of 1kfd by Molmil
CRYSTAL STRUCTURES OF THE KLENOW FRAGMENT OF DNA POLYMERASE I COMPLEXED WITH DEOXYNUCLEOSIDE TRIPHOSPHATE AND PYROPHOSPHATE
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I KLENOW FRAGMENT
Authors:Beese, L.S, Friedman, J.M, Steitz, T.A.
Deposit date:1993-09-23
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate.
Biochemistry, 32, 1993
1TFW
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BU of 1tfw by Molmil
How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
Descriptor: 5'-R(*CP*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*CP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
Authors:Xiong, Y, Steitz, T.A.
Deposit date:2004-05-27
Release date:2004-08-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
1TLF
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BU of 1tlf by Molmil
UNPRECEDENTED QUATERNARY STRUCTURE OF E. COLI LAC REPRESSOR CORE TETRAMER: IMPLICATIONS FOR DNA LOOPING
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, ETHYL MERCURY ION, LAC REPRESSOR
Authors:Friedman, A.M, Fischmann, T.O, Steitz, T.A.
Deposit date:1995-03-06
Release date:1995-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of lac repressor core tetramer and its implications for DNA looping.
Science, 268, 1995
1SZ1
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BU of 1sz1 by Molmil
Mechanism of CCA-adding enzymes specificity revealed by crystal structures of ternary complexes
Descriptor: T-RNA (76-MER), tRNA nucleotidyltransferase
Authors:Xiong, Y, Steitz, T.A.
Deposit date:2004-04-02
Release date:2004-08-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (6.21 Å)
Cite:Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004

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