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BRAF in Complex with RAF265
Descriptor:	1-methyl-5-({2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine, Serine/threonine-protein kinase B-raf
Authors:	Appleton, B.A.
Deposit date:	2015-07-23
Release date:	2015-09-09
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (3.17 Å)
Cite:	Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma. Acs Med.Chem.Lett., 6, 2015

Rsk2 N-terminal Kinase in Complex with bis-phenol pyrazole
Descriptor:	4,4'-(1H-pyrazole-3,4-diyl)diphenol, GLYCEROL, Ribosomal protein S6 kinase alpha-3
Authors:	Appleton, B.A.
Deposit date:	2015-08-18
Release date:	2015-09-02
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Discovery of Potent and Selective RSK Inhibitors as Biological Probes. J.Med.Chem., 58, 2015