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Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Descriptor:	1-[(4-chlorophenyl)methyl]-1H-benzimidazol-2-amine, FORMIC ACID, GLYCEROL, ...
Authors:	Phan, J, Fesik, S.W.
Deposit date:	2019-12-13
Release date:	2020-08-26
Last modified:	2024-11-13
Method:	X-RAY DIFFRACTION (1.849 Å)
Cite:	Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020

Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Descriptor:	1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazole, FORMIC ACID, GLYCEROL, ...
Authors:	Phan, J, Fesik, S.W.
Deposit date:	2019-12-13
Release date:	2020-08-26
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020

Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Descriptor:	3-(2-aminoethyl)-4-(3-chloro-4-fluorophenoxy)benzene-1-sulfonamide, FORMIC ACID, GLYCEROL, ...
Authors:	Phan, J, Fesik, S.W.
Deposit date:	2019-12-13
Release date:	2020-08-26
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (1.76 Å)
Cite:	Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020