5A6A
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![BU of 5a6a by Molmil](/molmil-images/mine/5a6a) | GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with NGT | Descriptor: | 1,2-ETHANEDIOL, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, N-ACETYL-BETA-D-GLUCOSAMINIDASE | Authors: | Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B. | Deposit date: | 2015-06-24 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. J. Biol. Chem., 290, 2015
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5A57
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![BU of 5a57 by Molmil](/molmil-images/mine/5a57) | The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT | Descriptor: | (Z)-[(3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-ylidene]amino] N-phenylcarbamate, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Gregg, K.J, Suits, M.D.L, Deng, L, Vocadlo, D.J, Boraston, A.B. | Deposit date: | 2015-06-16 | Release date: | 2015-09-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights Into its Mechanism. J.Biol.Chem., 290, 2015
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6QYV
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![BU of 6qyv by Molmil](/molmil-images/mine/6qyv) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A (Ser2, Ala5, Ala8) analogue | Descriptor: | PHE-SER-DAL-LEU-ALA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2019-10-02 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QTF
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![BU of 6qtf by Molmil](/molmil-images/mine/6qtf) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, major conformer | Descriptor: | DCY-LEU-GLY-ALA-THR | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-02-25 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYU
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![BU of 6qyu by Molmil](/molmil-images/mine/6qyu) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A | Descriptor: | PHE-DHA-DAL-LEU-DHA-LEU-CYS-ALA | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QM1
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![BU of 6qm1 by Molmil](/molmil-images/mine/6qm1) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Nisin Ring B (Lan8,11) analogue | Descriptor: | DAL-PRO-GLY-CYS-LYS | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-02-01 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6QYR
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![BU of 6qyr by Molmil](/molmil-images/mine/6qyr) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, minor conformer | Descriptor: | DAL-LEU-GLY-CYS-THR | Authors: | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | Deposit date: | 2019-03-09 | Release date: | 2019-09-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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5KPS
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![BU of 5kps by Molmil](/molmil-images/mine/5kps) | Structure of RelA bound to ribosome in absence of A/R tRNA (Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2016-07-05 | Release date: | 2016-09-28 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife, 5, 2016
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2L21
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![BU of 2l21 by Molmil](/molmil-images/mine/2l21) | chicken IGF2R domain 11 | Descriptor: | Cation-independent mannose-6-phosphate receptor | Authors: | Williams, C, Hoppe, H, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Rezgui, D.Z, Crump, M.P, Hassan, A.B. | Deposit date: | 2010-08-10 | Release date: | 2012-02-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | CD loop dependency of the IGF2: M6P/IGF2 receptor binding interaction predates imprinting To be Published
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2LM3
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![BU of 2lm3 by Molmil](/molmil-images/mine/2lm3) | Structure of the rhesus monkey TRIM5alpha PRYSPRY domain | Descriptor: | Tripartite motif-containing protein 5 | Authors: | Biris, N, Yang, Y, Taylor, A.B, Tomashevski, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D.N. | Deposit date: | 2011-11-21 | Release date: | 2012-08-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module. Proc.Natl.Acad.Sci.USA, 109, 2012
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2L29
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![BU of 2l29 by Molmil](/molmil-images/mine/2l29) | Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II | Descriptor: | Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II | Authors: | Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B. | Deposit date: | 2010-08-13 | Release date: | 2012-02-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science, 338, 2012
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5LA6
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![BU of 5la6 by Molmil](/molmil-images/mine/5la6) | Tubulin-pironetin complex | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Prota, A.E, Setter, J, Waight, A.B, Bargsten, K, Murga, J, Diaz, J.F, Steinmetz, M.O. | Deposit date: | 2016-06-13 | Release date: | 2016-07-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation. J.Mol.Biol., 428, 2016
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5LFY
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![BU of 5lfy by Molmil](/molmil-images/mine/5lfy) | |
2M6T
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![BU of 2m6t by Molmil](/molmil-images/mine/2m6t) | NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R | Descriptor: | Insulin-like growth factor 2 receptor variant | Authors: | Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. | Deposit date: | 2013-04-09 | Release date: | 2014-10-15 | Last modified: | 2016-06-01 | Method: | SOLUTION NMR | Cite: | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist. Proc.Natl.Acad.Sci.USA, 113, 2016
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7N5F
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![BU of 7n5f by Molmil](/molmil-images/mine/7n5f) | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Down' conformation in GDN | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | Deposit date: | 2021-06-05 | Release date: | 2022-02-16 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5D
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![BU of 7n5d by Molmil](/molmil-images/mine/7n5d) | Composite Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | Deposit date: | 2021-06-05 | Release date: | 2022-02-16 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5G
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![BU of 7n5g by Molmil](/molmil-images/mine/7n5g) | Structure of Mechanosensitive Ion Channel Flycatcher1 Protomer in 'Up' conformation in GDN | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | Deposit date: | 2021-06-05 | Release date: | 2022-02-16 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7N5E
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![BU of 7n5e by Molmil](/molmil-images/mine/7n5e) | Structure of Mechanosensitive Ion Channel Flycatcher1 in GDN | Descriptor: | Mechanosensitive ion channel Flycatcher1, PALMITIC ACID | Authors: | Jojoa-Cruz, S, Saotome, K, Lee, W.H, Patapoutian, A, Ward, A.B. | Deposit date: | 2021-06-05 | Release date: | 2022-02-16 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1. Nat Commun, 13, 2022
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7O5H
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![BU of 7o5h by Molmil](/molmil-images/mine/7o5h) | Ribosomal methyltransferase KsgA bound to small ribosomal subunit | Descriptor: | 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Stephan, N.C, Ries, A.B, Boehringer, D, Ban, N. | Deposit date: | 2021-04-08 | Release date: | 2021-06-16 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of successive adenosine modifications by the conserved ribosomal methyltransferase KsgA. Nucleic Acids Res., 49, 2021
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1MCL
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![BU of 1mcl by Molmil](/molmil-images/mine/1mcl) | PRINCIPLES AND PITFALLS in DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), N-ACETYL-D-HIS-L-PRO-OH | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCR
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![BU of 1mcr by Molmil](/molmil-images/mine/1mcr) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-HIS-D-PRO-OH | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCC
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![BU of 1mcc by Molmil](/molmil-images/mine/1mcc) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-NH2 | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCE
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![BU of 1mce by Molmil](/molmil-images/mine/1mce) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-OH | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2022-04-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCN
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![BU of 1mcn by Molmil](/molmil-images/mine/1mcn) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-D-HIS-L-PRO-NH2 | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCF
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![BU of 1mcf by Molmil](/molmil-images/mine/1mcf) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | Descriptor: | Immunoglobulin lambda-1 light chain, PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH | Authors: | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | Deposit date: | 1993-02-25 | Release date: | 1994-01-31 | Last modified: | 2022-04-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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