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4YWB
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BU of 4ywb by Molmil
Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and oxalic acid
Descriptor: 3-sulfanylpyridine-2-carboxylic acid, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Balan, M.D, Johnson, T.A, Lotosky, W.R, Mcleod, M.J, Holyoak, T.
Deposit date:2015-03-20
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid.
Biochemistry, 54, 2015
3DT2
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BU of 3dt2 by Molmil
The structure of rat cytosolic PEPCK in complex with oxalate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Sullivan, S.M, Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT4
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BU of 3dt4 by Molmil
The structure of rat cytosolic PEPCK in complex with oxalate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Sullivan, S.M, Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT7
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BU of 3dt7 by Molmil
The structure of rat cytosolic PEPCK in complex with beta-sulfopyruvate and GTP
Descriptor: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Sullivan, S.M, Holyoak, T.
Deposit date:2008-07-14
Release date:2008-08-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5FH3
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BU of 5fh3 by Molmil
The structure of rat cytosolic PEPCK variant E89A in complex with oxalic acid and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
5FH5
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BU of 5fh5 by Molmil
The structure of rat cytosolic PEPCK variant E89Q in complex with phosphoglycolate and GDP
Descriptor: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
8E1U
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BU of 8e1u by Molmil
Propionibacterium freudenreichii PPi-dependent PEPCK in complex with malate
Descriptor: D-MALATE, MAGNESIUM ION, PPi-dependent PEPCK
Authors:McLeod, M.J, Holyoak, T.
Deposit date:2022-08-11
Release date:2023-06-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Biochemical, structural, and kinetic characterization of PP i -dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii.
Proteins, 91, 2023
5FH1
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BU of 5fh1 by Molmil
The structure of rat cytosolic PEPCK variant E89D in complex with GTP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-12-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
5FH0
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BU of 5fh0 by Molmil
The structure of rat cytosolic PEPCK variant E89A complex with GTP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
5FH4
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BU of 5fh4 by Molmil
The structure of rat cytosolic PEPCK variant E89D in complex with beta-sulfopyruvate and GTP
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
5FH2
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BU of 5fh2 by Molmil
The structure of rat cytosolic PEPCK variant E89Q in complex with GTP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2015-12-21
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Biochemistry, 55, 2016
2QEY
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BU of 2qey by Molmil
Rat cytosolic PEPCK in complex with GTP
Descriptor: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Sullivan, S.M, Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QEW
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BU of 2qew by Molmil
Rat cytosolic PEPCK, in complex with manganese ion.
Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ...
Authors:Sullivan, S.M, Holyoak, T.
Deposit date:2007-06-26
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2RKD
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BU of 2rkd by Molmil
The Structure of rat cytosolic PEPCK in complex with 3-phosphonopropionate
Descriptor: 3-PHOSPHONOPROPANOIC ACID, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RK8
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BU of 2rk8 by Molmil
The Structure of rat cytosolic PEPCK in complex with phosphonoformate
Descriptor: DI(HYDROXYETHYL)ETHER, FORMIC ACID, MANGANESE (II) ION, ...
Authors:Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
4GMZ
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BU of 4gmz by Molmil
Structure of rat cytosolic PEPCK Ld_2g in complex with Beta-Sulfopyruvate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-16
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
2RKA
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BU of 2rka by Molmil
The Structure of rat cytosolic PEPCK in complex with phosphoglycolate
Descriptor: 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RKE
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BU of 2rke by Molmil
The Structure of rat cytosolic PEPCK in complex with sulfoacetate.
Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ...
Authors:Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
2RK7
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BU of 2rk7 by Molmil
The Structure of rat cytosolic PEPCK in complex with oxalate
Descriptor: MANGANESE (II) ION, OXALATE ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T.
Deposit date:2007-10-16
Release date:2008-01-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Biochemistry, 47, 2008
4GNP
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BU of 4gnp by Molmil
Structure of rat cytosolic PEPCK Ld_3g in complex with PEP and GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-17
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.744 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
4GNM
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BU of 4gnm by Molmil
Structure of rat cytosolic PEPCK Ld_2g in complex with oxalate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-17
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
4GMU
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BU of 4gmu by Molmil
Structure of rat cytosolic PEPCK Ld_1g in complex with oxalate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-16
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
4GNQ
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BU of 4gnq by Molmil
Structure of rat cytosolic PEPCK Ld_3g in complex with oxalate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-17
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
4GNO
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BU of 4gno by Molmil
Structure of rat cytosolic PEPCK Ld_3g in complex with Beta-Sulfopyruvate and GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PENTAETHYLENE GLYCOL, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-17
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012
4GNL
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BU of 4gnl by Molmil
Structure of rat cytosolic PEPCK Ld_2g in complex with PEP and GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Johnson, T.A, Holyoak, T.
Deposit date:2012-08-17
Release date:2013-07-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Biochemistry, 51, 2012

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