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7B94
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BU of 7b94 by Molmil
MEK1 in complex with compound 6
Descriptor: 2-(4-iodophenyl)-8~{H}-imidazo[1,2-c]pyrimidin-5-one, Dual specificity mitogen-activated protein kinase kinase 1,Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ...
Authors:Kack, H, Oster, L.
Deposit date:2020-12-14
Release date:2021-03-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragment-Based Discovery of Novel Allosteric MEK1 Binders.
Acs Med.Chem.Lett., 12, 2021
5NMZ
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BU of 5nmz by Molmil
human Neurturin (97-197)
Descriptor: GLYCEROL, Neurturin
Authors:Bigalke, J.M, Sandmark, J, Roth, R.
Deposit date:2017-04-07
Release date:2018-02-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
J. Biol. Chem., 293, 2018
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