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Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.459144 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFF

Human dihydroorotase mutant F1563Y apo structure
Descriptor:	CAD protein, FORMIC ACID, ZINC ION
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.51000106 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFQ

Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.1454246 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFN

Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.44965148 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFH

Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.44871271 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFR

Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.29949379 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFE

Human dihydroorotase mutant F1563T apo structure
Descriptor:	CAD protein, FORMIC ACID, ZINC ION
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.47997439 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFU

Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.3997103 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFL

Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFI

Human dihydroorotase mutant F1563A apo structure
Descriptor:	CAD protein, FORMIC ACID, ZINC ION
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.45994723 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFJ

Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.2 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFS

Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5
Descriptor:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.34904516 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

6HFP

Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0
Descriptor:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
Authors:	Ramon-Maiques, S, Grande Garcia, A.
Deposit date:	2018-08-21
Release date:	2018-10-24
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (1.1982286 Å)
Cite:	Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018

5NNL

Inactive dihydroorotase-like domain of Chaetomium thermophilum CAD-like multifunctional protein
Descriptor:	Inactive dihydroorotase-like domain
Authors:	Ramon-Maiques, S, Moreno-Morcillo, M, Grande-Garcia, A.
Deposit date:	2017-04-10
Release date:	2017-06-07
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.13 Å)
Cite:	Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis. Structure, 25, 2017

6YPO

Arabidopsis aspartate transcarbamoylase bound to UMP
Descriptor:	GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-16
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.67 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YS6

Arabidopsis aspartate transcarbamoylase complex with PALA
Descriptor:	GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB, ...
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-21
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YSP

Arabidopsis aspartate transcarbamoylase complex with PALA and carbamoyl phosphate
Descriptor:	GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-23
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.38 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YW9

Arabidopsis aspartate transcarbamoylase mutant F161A complex with PALA
Descriptor:	GLYCEROL, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, PYRB
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-29
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YVB

Arabidopsis aspartate transcarbamoylase complex with carbamoyl phosphate
Descriptor:	ACETATE ION, GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-28
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (1.826 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YY1

Arabidopsis aspartate transcarbamoylase in apo state
Descriptor:	GLYCEROL, PYRB
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-05-04
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (3.06 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

6YWJ

Arabidopsis aspartate transcarbamoylase mutant F161A complex with UMP
Descriptor:	GLYCEROL, PYRB, URIDINE-5'-MONOPHOSPHATE
Authors:	Ramon Maiques, S, Del Cano Ochoa, F, Bellin, L, Mohlmann, T.
Deposit date:	2020-04-29
Release date:	2021-03-03
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat Commun, 12, 2021

5NNQ

Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
Descriptor:	GLYCEROL, ctATC
Authors:	Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
Deposit date:	2017-04-10
Release date:	2017-06-07
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.26 Å)
Cite:	Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis. Structure, 25, 2017

5NNN

Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like
Descriptor:	GLYCEROL, ctATC
Authors:	Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
Deposit date:	2017-04-10
Release date:	2017-06-07
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.26 Å)
Cite:	Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis. Structure, 25, 2017

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Displayed results:	23
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