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4N1Y
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BU of 4n1y by Molmil
Crystal Structure of the Pacific Oyster Estrogen Receptor Ligand Binding Domain
Descriptor: Estrogen receptor
Authors:Ortlund, E.O.
Deposit date:2013-10-04
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor.
PLoS Genet, 10, 2014
4OND
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BU of 4ond by Molmil
Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex
Descriptor: 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*G)-3', Ancestral SR2 Helix Mutant, ...
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2014-01-28
Release date:2014-10-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
Cell(Cambridge,Mass.), 159, 2014
1YMT
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BU of 1ymt by Molmil
Mouse SF-1 LBD
Descriptor: 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1
Authors:Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
Deposit date:2005-01-21
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Cell(Cambridge,Mass.), 120, 2005
2Q1V
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BU of 2q1v by Molmil
Ancestral corticoid receptor in complex with cortisol
Descriptor: 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, AncCR, GLYCEROL
Authors:Ortlund, E.A, Redinbo, M.R.
Deposit date:2007-05-25
Release date:2007-09-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of an ancient protein: evolution by conformational epistasis.
Science, 317, 2007
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