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5R1R
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BU of 5r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441A MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
7R1R
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BU of 7r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441Q MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
4R1R
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BU of 4r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI
Descriptor: GUANOSINE-5'-DIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, ...
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-07-22
Release date:1998-01-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
6R1R
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BU of 6r1r by Molmil
RIBONUCLEOTIDE REDUCTASE E441D MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
1HK8
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BU of 1hk8 by Molmil
STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE, MANGANESE (II) ION, ...
Authors:Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T.
Deposit date:2003-03-06
Release date:2003-03-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Metal-Binding Site in the Catalytic Subunit of Anaerobic Ribonucleotide Reductase.
Proc.Natl.Acad.Sci.USA, 100, 2003
1R1R
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BU of 1r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI
Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-07-15
Release date:1998-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
6ZJK
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BU of 6zjk by Molmil
Ribonucleotide reductase R2 subunit from Clostridium botulinum
Descriptor: FE (III) ION, GLYCEROL, Ribonucleoside-diphosphate reductase subunit beta
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2020-06-29
Release date:2020-09-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site.
J.Biol.Chem., 295, 2020
3DHZ
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BU of 3dhz by Molmil
Apo (iron free) structure of C. ammoniagenes R2 protein
Descriptor: FE (II) ION, Ribonucleotide reductase subunit R2F
Authors:Hogbom, M, Nordlund, P.
Deposit date:2008-06-19
Release date:2008-07-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural and mutational studies of the carboxylate cluster in Iron-free Ribonucleotide Reductase R2.
Biochemistry, 43, 2004
7AIL
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BU of 7ail by Molmil
Ribonucleotide Reductase R2m protein from Aquifex aeolicus
Descriptor: FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Rehling, D, Scaletti, E.R, Stenmark, P.
Deposit date:2020-09-27
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
7AGJ
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BU of 7agj by Molmil
Ribonucleotide Reductase R1 protein from Aquifex aeolicus
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Rehling, D, Scaletti, E.R, Stenmark, P.
Deposit date:2020-09-22
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
7AIK
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BU of 7aik by Molmil
Ribonucleotide Reductase R2 protein from Aquifex aeolicus
Descriptor: FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta,Ribonucleoside-diphosphate reductase subunit beta
Authors:Rehling, D, Scaletti, E.R, Stenmark, P.
Deposit date:2020-09-27
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
5IM3
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BU of 5im3 by Molmil
Crystal structure of the class I ribonucleotide reductase from Pseudomonas aeruginosa in complex with dATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase
Authors:Johansson, R, Logan, D.T.
Deposit date:2016-03-05
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones.
Structure, 24, 2016
8BT3
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BU of 8bt3 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, catalytically active radical state solved by XFEL
Descriptor: Ribonucleoside-diphosphate reductase beta chain
Authors:Lebrette, H, Srinivas, V, Hogbom, M.
Deposit date:2022-11-27
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a ribonucleotide reductase R2 protein radical.
Science, 382, 2023
8BT4
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BU of 8bt4 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, radical-lost ground state
Descriptor: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase
Authors:Lebrette, H, Srinivas, V, Hogbom, M.
Deposit date:2022-11-27
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of a ribonucleotide reductase R2 protein radical.
Science, 382, 2023
3R1R
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BU of 3r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-07-21
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
2R1R
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BU of 2r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI
Descriptor: RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE
Authors:Eriksson, M, Eklund, H.
Deposit date:1997-07-21
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
7P37
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BU of 7p37 by Molmil
Streptomyces coelicolor ATP-loaded NrdR
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ZINC ION
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-07
Release date:2022-05-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
7P3Q
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BU of 7p3q by Molmil
Streptomyces coelicolor dATP/ATP-loaded NrdR octamer
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-08
Release date:2022-05-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
7P3F
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BU of 7p3f by Molmil
Streptomyces coelicolor dATP/ATP-loaded NrdR in complex with its cognate DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Martinez-Carranza, M, Stenmark, P.
Deposit date:2021-07-07
Release date:2022-05-11
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
7Q39
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BU of 7q39 by Molmil
Ribonucleotide Reductase R2_genomic protein from Aquifex aeolicus
Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Scaletti, E, Rehling, D, Stenmark, P.
Deposit date:2021-10-27
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
7Q3C
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BU of 7q3c by Molmil
Ribonucleotide Reductase AaR2 protein from Aquifex aeolicus
Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Scaletti, E.R, Rehling, D, Stenmark, P.
Deposit date:2021-10-27
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus.
Biochemistry, 61, 2022
1RNR
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BU of 1rnr by Molmil
AUTOCATALYTIC GENERATION OF DOPA IN THE ENGINEERED PROTEIN R2 F208Y FROM ESCHERICHIA COLI RIBONUCLEOTIDE REDUCTASE AND CRYSTAL STRUCTURE OF THE DOPA-208 PROTEIN
Descriptor: FE (III) ION, MERCURY (II) ION, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN
Authors:Aberg, A, Nordlund, P.
Deposit date:1993-04-26
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autocatalytic generation of dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the dopa-208 protein.
Biochemistry, 32, 1993
2XAZ
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BU of 2xaz by Molmil
Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-04-01
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XAX
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BU of 2xax by Molmil
Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-04-01
Release date:2010-04-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
2XO5
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BU of 2xo5 by Molmil
RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI
Descriptor: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J.
Deposit date:2010-08-09
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases.
J.Am.Chem.Soc., 133, 2011

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