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Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with compound 9, a novel nanomolar A2A receptor antagonist from modern hit-finding with structure-guided de novo design
Descriptor:	2-(furan-2-yl)-7-pyridin-4-yl-pyrrolo[2,3-d]pyrimidin-4-amine, Adenosine receptor A2a,Soluble cytochrome b562, CHOLESTEROL, ...
Authors:	Tian, G, Maja, N.
Deposit date:	2024-10-15
Release date:	2025-06-18
Method:	X-RAY DIFFRACTION (1.715 Å)
Cite:	Identification of nanomolar adenosine A2A receptor ligands using reinforcement learning and structure-based drug design To Be Published