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5W6M
Crystal structure of the human histidyl-tRNA synthetase mutant D175E
Descriptor:
Histidine--tRNA ligase, cytoplasmic
Authors:
Blocquel, D
,
Yang, X.L.
Deposit date:
2017-06-16
Release date:
2018-06-20
Last modified:
2023-10-04
Method:
X-RAY DIFFRACTION (3.696 Å)
Cite:
CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells.
Proc.Natl.Acad.Sci.USA, 2019
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PDB entries from 2024-11-13