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3E8K
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BU of 3e8k by Molmil
Crystal structure of HK97 Prohead II
Descriptor: Major capsid protein
Authors:Gertsman, I, Speir, J, Johnson, J.E.
Deposit date:2008-08-20
Release date:2009-02-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:An unexpected twist in viral capsid maturation.
Nature, 458, 2009
5WE2
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BU of 5we2 by Molmil
Structural Basis for Telomere Length Regulation by the Shelterin Bridge
Descriptor: DNA-binding protein rap1, Protection of telomeres protein poz1, Protection of telomeres protein tpz1, ...
Authors:Kim, J.-K, Liu, J, Hu, X, Sankaran, B, Qiao, F.
Deposit date:2017-07-06
Release date:2017-12-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Shelterin Bridge Assembly.
Mol. Cell, 68, 2017
2GP1
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BU of 2gp1 by Molmil
Bacteriophage HK97 Prohead II crystal structure
Descriptor: Major capsid protein
Authors:Gertsman, I, Gan, L, Johnson, J.E.
Deposit date:2006-04-15
Release date:2006-05-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.2 Å)
Cite:Structure and Flexibility of Bacteriophage HK97 Pre-expanded State Prohead II
To be Published
6OCE
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BU of 6oce by Molmil
Structure of the rice hyperosmolality-gated ion channel OSCA1.2
Descriptor: stress-gated cation channel 1.2
Authors:Maity, K, Heumann, J.M, McGrath, A.P, Chang, G, Stowell, M.H.
Deposit date:2019-03-23
Release date:2019-07-03
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Cryo-EM structure of OSCA1.2 fromOryza sativaelucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc.Natl.Acad.Sci.USA, 116, 2019
8VHE
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BU of 8vhe by Molmil
Crystal Structure of Human IDH1 R132Q in Complex with NADPH-TCEP Adduct
Descriptor: 3,3',3''-({(4R)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1,4-dihydropyridin-4-yl}-lambda~5~-phosphanetriyl)tripropanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHB
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BU of 8vhb by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Alpha-Ketoglutarate
Descriptor: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, 2-OXOGLUTARIC ACID, CALCIUM ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VH9
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BU of 8vh9 by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH
Descriptor: CITRIC ACID, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHD
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BU of 8vhd by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Isocitrate
Descriptor: CALCIUM ION, GLYCEROL, IODIDE ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHA
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BU of 8vha by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH and Alpha-Ketoglutarate
Descriptor: (3~{S})-3-[(4~{S})-3-aminocarbonyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-[[[[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4~{H}-pyridin-4-yl]-2-oxidanylidene-pentanedioic acid, 2-OXOGLUTARIC ACID, CALCIUM ION, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
8VHC
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BU of 8vhc by Molmil
Crystal Structure of Human IDH1 R132Q in complex with NADPH
Descriptor: GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Mealka, M, Sohl, C.D, Huxford, T.
Deposit date:2023-12-31
Release date:2024-04-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Nat Commun, 15, 2024
5LHP
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BU of 5lhp by Molmil
The p-aminobenzamidine active site inhibited catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7
Descriptor: 1,2-ETHANEDIOL, Camelid-Derived Antibody Fragment, P-AMINO BENZAMIDINE, ...
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017
5LHN
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BU of 5lhn by Molmil
The catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7
Descriptor: 1,2-ETHANEDIOL, Camelid-Derived Antibody Fragment Nb7, SULFATE ION, ...
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017
5LHQ
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BU of 5lhq by Molmil
The EGR-cmk active site inhibited catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7
Descriptor: 1,2-ETHANEDIOL, Camelid-Derived Antibody Fragment Nb7, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ...
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017
5LHS
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BU of 5lhs by Molmil
The ligand free catalytic domain of murine urokinase-type plasminogen activator
Descriptor: NICKEL (II) ION, SULFATE ION, Urokinase-type plasminogen activator
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.047 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017
5LHR
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BU of 5lhr by Molmil
The catalytic domain of murine urokinase-type plasminogen activator in complex with the active site binding inhibitory nanobody Nb22
Descriptor: Camelid-Derived Antibody Fragment Nb22, Urokinase-type plasminogen activator
Authors:Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A.
Deposit date:2016-07-12
Release date:2017-06-28
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep, 7, 2017
1EGT
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BU of 1egt by Molmil
THROMBIN-BOUND STRUCTURE OF AN EGF SUBDOMAIN FROM HUMAN THROMBOMODULIN DETERMINED BY TRANSFERRED NUCLEAR OVERHAUSER EFFECTS
Descriptor: THROMBOMODULIN
Authors:Ni, F.
Deposit date:1994-10-12
Release date:1995-11-15
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects.
Biochemistry, 33, 1994
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