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Human cyclic GMP-AMP synthase (cGAS) in complex with 2',5'-GpAp
Descriptor:	2',5'-GpAp, Cyclic GMP-AMP synthase, ZINC ION
Authors:	Byrnes, L.J, Hall, J.D.
Deposit date:	2017-04-03
Release date:	2017-09-27
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.246 Å)
Cite:	The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017

Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cdIMP
Descriptor:	3',3'-cdIMP, Cyclic GMP-AMP synthase, ZINC ION
Authors:	Byrnes, L.J, Hall, J.D.
Deposit date:	2017-04-03
Release date:	2017-09-27
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.042 Å)
Cite:	The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017

Human cyclic GMP-AMP synthase (cGAS) in complex with 2',3'-cGAMP
Descriptor:	Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION, ...
Authors:	Byrnes, L.J, Hall, J.D.
Deposit date:	2017-04-03
Release date:	2017-09-27
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017