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A soakable crystal form of human CDK7 in complex with AMP-PNP
Descriptor:	3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Cyclin-dependent kinase 7, DI(HYDROXYETHYL)ETHER, ...
Authors:	Mukherjee, M, Cleasby, A.
Deposit date:	2023-11-30
Release date:	2024-05-29
Last modified:	2024-06-26
Method:	X-RAY DIFFRACTION (2.78 Å)
Cite:	Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design. Structure, 2024

A soakable crystal form of human CDK7 in complex with AMP-PNP
Descriptor:	7-dimethylphosphoryl-3-[2-[[(3~{S})-6,6-dimethylpiperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1~{H}-indole-6-carbonitrile, Cyclin-dependent kinase 7
Authors:	Mukherjee, M, Cleasby, A.
Deposit date:	2023-11-30
Release date:	2024-05-29
Last modified:	2024-06-26
Method:	X-RAY DIFFRACTION (1.937 Å)
Cite:	Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design. Structure, 2024