6G81
 
 | | Solution structure of the Ni metallochaperone HypA from Helicobacter pylori | | Descriptor: | Hydrogenase maturation factor HypA, ZINC ION | | Authors: | Spronk, C.A.E.M, Zerko, S, Gorka, M, Kozminski, W, Bardiaux, B, Zambelli, B, Musiani, F, Piccioli, M, Hu, H, Maroney, M, Ciurli, S. | | Deposit date: | 2018-04-07 | | Release date: | 2018-10-10 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Structure and dynamics of Helicobacter pylori nickel-chaperone HypA: an integrated approach using NMR spectroscopy, functional assays and computational tools.
J. Biol. Inorg. Chem., 23, 2018
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7B5A
 | | X-ray crystal structure of Sporosarcina pasteurii urease inhibited by Ag(PEt3)2NO3 determined at 1.97 Angstroms | | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2020-12-03 | | Release date: | 2021-10-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag(I) complexes.
J.Inorg.Biochem., 218, 2021
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7B58
 | | X-ray crystal structure of Sporosarcina pasteurii urease inhibited by Ag(PEt3)Cl determined at 1.72 Angstroms | | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2020-12-03 | | Release date: | 2021-10-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag(I) complexes.
J.Inorg.Biochem., 218, 2021
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7B59
 | | X-ray crystal structure of Sporosarcina pasteurii urease inhibited by Ag(PEt3)Br determined at 1.63 Angstroms | | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2020-12-03 | | Release date: | 2021-10-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag(I) complexes.
J.Inorg.Biochem., 218, 2021
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5N76
 | | Crystal structure of the apo-form of the CO dehydrogenase accessory protein CooT from Rhodospirillum rubrum | | Descriptor: | CooT | | Authors: | Timm, J, Brochier-Armanet, C, Perard, J, Zambelli, B, Ollagnier-de-Choudens, S, Ciurli, S, Cavazza, C. | | Deposit date: | 2017-02-19 | | Release date: | 2017-05-10 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The CO dehydrogenase accessory protein CooT is a novel nickel-binding protein.
Metallomics, 9, 2017
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6G48
 | | Sporosarcina pasteurii urease inhibited by silver | | Descriptor: | 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2018-03-27 | | Release date: | 2019-01-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | The structure of urease inactivated by Ag(i): a new paradigm for enzyme inhibition by heavy metals.
Dalton Trans, 47, 2018
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7P6F
 | | 1.93 A resolution X-ray crystal structure of the transcriptional regulator SrnR from Streptomyces griseus | | Descriptor: | ACETATE ION, SODIUM ION, Transcriptional regulator SrnR | | Authors: | Mazzei, L, Ciurli, S. | | Deposit date: | 2021-07-16 | | Release date: | 2022-05-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression.
Metallomics, 13, 2021
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1JXF
 | | SOLUTION STRUCTURE OF REDUCED CU(I) PLASTOCYANIN FROM SYNECHOCYSTIS PCC6803 | | Descriptor: | COPPER (II) ION, PLASTOCYANIN | | Authors: | Bertini, I, Bryant, D.A, Ciurli, S, Dikiy, A, Fernandez, C.O, Luchinat, C, Safarov, N, Vila, A.J, Zhao, J. | | Deposit date: | 2001-09-07 | | Release date: | 2001-09-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Backbone dynamics of plastocyanin in both oxidation states. Solution structure of the reduced form and comparison with the oxidized state.
J.Biol.Chem., 276, 2001
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1JXD
 | | SOLUTION STRUCTURE OF REDUCED CU(I) PLASTOCYANIN FROM SYNECHOCYSTIS PCC6803 | | Descriptor: | COPPER (II) ION, PLASTOCYANIN | | Authors: | Bertini, I, Bryant, D.A, Ciurli, S, Dikiy, A, Fernandez, C.O, Luchinat, C, Safarov, N, Vila, A.J, Zhao, J. | | Deposit date: | 2001-09-07 | | Release date: | 2001-09-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Backbone dynamics of plastocyanin in both oxidation states. Solution structure of the reduced form and comparison with the oxidized state.
J.Biol.Chem., 276, 2001
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6HK5
 | | X-ray structure of a truncated mutant of the metallochaperone CooJ with a high-affinity nickel-binding site | | Descriptor: | 3,3',3''-phosphoryltripropanoic acid, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Alfano, M, Perard, J, Basset, C, Carpentier, P, Zambelli, B, Timm, J, Crouzy, S, Ciurli, S, Cavazza, C. | | Deposit date: | 2018-09-05 | | Release date: | 2019-03-27 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.042 Å) | | Cite: | The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni(II)-binding site.
J.Biol.Chem., 294, 2019
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5OL4
 | | 1.28 A resolution of Sporosarcina pasteurii urease inhibited in the presence of NBPT | | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, Phosphoramidothioic O,O-acid, ... | | Authors: | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | | Deposit date: | 2017-07-26 | | Release date: | 2018-03-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Urease Inhibition in the Presence of N-(n-Butyl)thiophosphoric Triamide, a Suicide Substrate: Structure and Kinetics.
Biochemistry, 56, 2017
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2J8W
 | | The crystal structure of cytochrome c' from Rubrivivax gelatinosus at 1.3 A Resolution and pH 8.0 | | Descriptor: | CYTOCHROME C', HEME C | | Authors: | Benini, S, Ciurli, S, Rypniewski, W.R, Wilson, K.S. | | Deposit date: | 2006-10-30 | | Release date: | 2007-11-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | High resolution crystal structure of Rubrivivax gelatinosus cytochrome c'.
J. Inorg. Biochem., 102, 2008
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7P7N
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7P7O
 | | X-RAY CRYSTAL STRUCTURE OF SPOROSARCINA PASTEURII UREASE INHIBITED BY THE GOLD(I)-DIPHOSPHINE COMPOUND Au(PEt3)2Cl DETERMINED AT 1.87 ANGSTROMS | | Descriptor: | 1,2-ETHANEDIOL, NICKEL (II) ION, OXYGEN ATOM, ... | | Authors: | Mazzei, L, Ciurli, S, Cianci, M, Messori, L, Massai, L. | | Deposit date: | 2021-07-20 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Medicinal Au(I) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition.
Dalton Trans, 50, 2021
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6I9Y
 | | The 2.14 A X-ray crystal structure of Sporosarcina pasteurii urease in complex with Au(I) ions | | Descriptor: | 1,2-ETHANEDIOL, GOLD ION, HYDROXIDE ION, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2018-11-26 | | Release date: | 2019-05-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Inhibition Mechanism of Urease by Au(III) Compounds Unveiled by X-ray Diffraction Analysis.
Acs Med.Chem.Lett., 10, 2019
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5FSD
 | | 1.75 A resolution 2,5-dihydroxybenzensulfonate inhibited Sporosarcina pasteurii urease | | Descriptor: | 1,2-ETHANEDIOL, 2,5-dihydroxybenzenesulfonic acid, HYDROXIDE ION, ... | | Authors: | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface.
Dalton Trans, 45, 2016
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6H8J
 | | 1.45 A resolution of Sporosarcina pasteurii urease inhibited in the presence of NBPTO | | Descriptor: | 1,2-ETHANEDIOL, DIAMIDOPHOSPHATE, NICKEL (II) ION, ... | | Authors: | Mazzei, L, Cianci, M, Ciurli, S. | | Deposit date: | 2018-08-02 | | Release date: | 2019-06-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Insights into Urease Inhibition by N-( n-Butyl) Phosphoric Triamide through an Integrated Structural and Kinetic Approach.
J.Agric.Food Chem., 67, 2019
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5G4H
 | | 1.50 A resolution catechol (1,2-dihydroxybenzene) inhibited Sporosarcina pasteurii urease | | Descriptor: | 1,2-ETHANEDIOL, CATECHOL, HYDROXIDE ION, ... | | Authors: | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | | Deposit date: | 2016-05-13 | | Release date: | 2016-12-07 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Inactivation of Urease by Catechol: Kinetics and Structure.
J.Inorg.Biochem., 166, 2016
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5FSE
 | | 2.07 A resolution 1,4-Benzoquinone inhibited Sporosarcina pasteurii urease | | Descriptor: | 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... | | Authors: | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | | Deposit date: | 2016-01-04 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Inactivation of Urease by 1,4-Benzoquinone: Chemistry at the Protein Surface.
Dalton Trans, 45, 2016
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2MM8
 | | Structural and biochemical characterization of Jaburetox | | Descriptor: | Urease | | Authors: | Dobrovolska, O, Lopez, F, Ciurli, S, Zambelli, B, Carlini, C. | | Deposit date: | 2014-03-12 | | Release date: | 2015-01-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | 1H, 13C, 15N resonance assignments of reduced Jaburetox
To be Published
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4L3K
 | | Crystal structure of Sporosarcina pasteurii UreE bound to Ni2+ and Zn2+ | | Descriptor: | NICKEL (II) ION, Urease accessory protein UreE, ZINC ION | | Authors: | Zambelli, B, Banaszak, K, Merloni, A, Kiliszek, A, Rypniewski, W.R, Ciurli, S. | | Deposit date: | 2013-06-06 | | Release date: | 2013-10-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Selectivity of Ni(II) and Zn(II) binding to Sporosarcina pasteurii UreE, a metallochaperone in the urease assembly: a calorimetric and crystallographic study.
J.Biol.Inorg.Chem., 18, 2013
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3TJA
 | | Crystal structure of Helicobacter pylori UreE in the apo form | | Descriptor: | CHLORIDE ION, SULFATE ION, Urease accessory protein ureE | | Authors: | Banaszak, K, Bellucci, M, Zambelli, B, Rypniewski, W.R, Ciurli, S. | | Deposit date: | 2011-08-24 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking.
Biochem.J., 441, 2012
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3TJ9
 | | Crystal structure of Helicobacter pylori UreE bound to Zn2+ | | Descriptor: | FORMIC ACID, Urease accessory protein ureE, ZINC ION | | Authors: | Banaszak, K, Bellucci, M, Zambelli, B, Rypniewski, W.R, Ciurli, S. | | Deposit date: | 2011-08-24 | | Release date: | 2011-11-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.521 Å) | | Cite: | Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking.
Biochem.J., 441, 2012
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3TJ8
 | | Crystal structure of Helicobacter pylori UreE bound to Ni2+ | | Descriptor: | FORMIC ACID, NICKEL (II) ION, Urease accessory protein ureE | | Authors: | Banaszak, K, Bellucci, M, Zambelli, B, Rypniewski, W.R, Ciurli, S. | | Deposit date: | 2011-08-24 | | Release date: | 2011-11-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.591 Å) | | Cite: | Crystallographic and X-ray absorption spectroscopic characterization of Helicobacter pylori UreE bound to Ni2+ and Zn2+ reveals a role for the disordered C-terminal arm in metal trafficking.
Biochem.J., 441, 2012
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6ZNZ
 | | 1.89 A resolution 4-methylcatechol (4-methylbenzene-1,2-diol) inhibited Sporosarcina pasteurii urease | | Descriptor: | 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... | | Authors: | Mazzei, L, Cianci, M, Musiani, F, Ciurli, S. | | Deposit date: | 2020-07-07 | | Release date: | 2020-12-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies.
Angew.Chem.Int.Ed.Engl., 60, 2021
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