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2RGD
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BU of 2rgd by Molmil
Crystal structure of H-RasQ61L-GppNHp
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Buhrman, G, Wink, G, Mattos, C.
Deposit date:2007-10-03
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
6DZH
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BU of 6dzh by Molmil
HRAS G13D bound to GDP (H13GDP)
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GLYCEROL, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-04
Release date:2019-07-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
6E6F
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BU of 6e6f by Molmil
KRAS G13D bound to GppNHp (K13GNP)
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-24
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
6E6G
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BU of 6e6g by Molmil
KRAS G13D bound to GDP (K13GDP)
Descriptor: CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-24
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
4RSG
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BU of 4rsg by Molmil
Neutron crystal structure of Ras bound to the GTP analogue GppNHp
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Knihtila, R.R, Holzapfel, G, Weiss, K.L, Meilleur, F, Mattos, C.
Deposit date:2014-11-07
Release date:2015-11-04
Last modified:2024-02-28
Method:NEUTRON DIFFRACTION (1.907 Å)
Cite:Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP gamma-Phosphate.
J.Biol.Chem., 290, 2015
4XVR
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BU of 4xvr by Molmil
H-Ras Y137F
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2015-01-27
Release date:2015-06-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding.
Faseb J., 29, 2015
8EM0
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BU of 8em0 by Molmil
HRAS R97V Crystal Form 1
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2022-09-26
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.109 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELT
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BU of 8elt by Molmil
HRAS R97G Crystal Form 2
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2022-09-26
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
3V4F
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BU of 3v4f by Molmil
H-Ras PEG 400/CaCl2, ordered off
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ...
Authors:Holzapfel, G, Mattos, C.
Deposit date:2011-12-14
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.391 Å)
Cite:Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition.
Biochemistry, 51, 2012
2P1H
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BU of 2p1h by Molmil
Rapid Folding and Unfolding of Apaf-1 CARD
Descriptor: Apoptotic protease-activating factor 1, ZINC ION
Authors:Milam, S.L, Nicely, N.I, Feeney, B, Mattos, C, Clark, A.C.
Deposit date:2007-03-05
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Rapid Folding and Unfolding of Apaf-1 CARD.
J.Mol.Biol., 369, 2007
4G3X
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BU of 4g3x by Molmil
Crystal Structure of Q61L H-Ras-GppNHp bound to the RBD of Raf Kinase
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fetics, S.K, Kearney, B.M, Buhrman, G, Mattos, C.
Deposit date:2012-07-15
Release date:2013-07-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD.
Structure, 23, 2015
4G0N
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BU of 4g0n by Molmil
Crystal Structure of wt H-Ras-GppNHp bound to the RBD of Raf Kinase
Descriptor: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, ACETATE ION, CALCIUM ION, ...
Authors:Fetics, S.K, Kearney, B.M, Buhrman, G, Mattos, C.
Deposit date:2012-07-09
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD.
Structure, 23, 2015
3ITN
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BU of 3itn by Molmil
Crystal structure of Pseudo-activated Procaspase-3
Descriptor: ACETYL-ASP-GLU-VAL-ASP-CHLOROMETHYL KETONE inhibitor, Caspase-3
Authors:Walters, J, Pop, C, Scott, F.L, Drag, M, Swartz, P.D, Mattos, C, Salvesen, G.S, Clark, A.C.
Deposit date:2009-08-28
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.
Biochem.J., 424, 2009
6E6P
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BU of 6e6p by Molmil
HRAS G13D bound to GppNHp (Ha,b,c13GNP)
Descriptor: CALCIUM ION, GLYCEROL, GTPase HRas, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-25
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
6E6C
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BU of 6e6c by Molmil
HRAS G13D bound to GppNHp (H13GNP)
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-24
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
6E6H
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BU of 6e6h by Molmil
NRAS G13D bound to GppNHp (N13GNP)
Descriptor: GTPase NRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Johnson, C.W, Mattos, C.
Deposit date:2018-07-24
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D.
Cell Rep, 28, 2019
5UHV
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BU of 5uhv by Molmil
wild-type NRas bound to GppNHp
Descriptor: GLYCEROL, GTPase NRas, MAGNESIUM ION, ...
Authors:Reid, D, Johnson, C, Salter, S, Mattos, C.
Deposit date:2017-01-12
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.672 Å)
Cite:The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects.
J. Biol. Chem., 292, 2017
1U8Y
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BU of 1u8y by Molmil
CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
1U8Z
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BU of 1u8z by Molmil
Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
1U90
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BU of 1u90 by Molmil
Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
8FG3
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BU of 8fg3 by Molmil
HRAS R97L Crystal Form 2
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Fetics, S, Johnson, C.W, Mattos, C.
Deposit date:2022-12-12
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8FG4
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BU of 8fg4 by Molmil
HRAS R97L Crystal Form 1
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Fetics, S, Johnson, C.W, Mattos, C.
Deposit date:2022-12-12
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELY
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BU of 8ely by Molmil
HRAS R97M Crystal Form 2
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2022-09-26
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELV
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BU of 8elv by Molmil
HRAS R97I Crystal Form 2
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Johnson, C.W, Mattos, C.
Deposit date:2022-09-26
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
8ELS
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BU of 8els by Molmil
HRAS R97A Crystal Form 1 R-state
Descriptor: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
Authors:Davis, D, Johnson, C.W, Mattos, C.
Deposit date:2022-09-26
Release date:2023-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.267 Å)
Cite:Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023

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