 | | PRD_000201 | | Name: | Alpha-Amanitin | | Formula: | C39 H54 N10 O14 S | | Description: | ALPHA-AMANITIN, IS AN 8 AMINO-ACID PEPTIDE.
THE OUTER LOOP IS FORMED BY A PEPTIDE BOND
BETWEEN THE C- AND THE N-TERMINI. THE SIDE-CHAINS
OF RESIDUES 2 AND 8 ARE LINKED TO FORM THE INNER
LOOP. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000203 | | Name: | Chloroorienticin A | | Formula: | C73 H88 Cl2 N10 O26 | | Description: | CHLOROORIENTICIN A IS A TRICYCLIC GLYCOPEPTIDE, GLYCOSYLATED BY ONE DISACCHARIDE ON RESIDUE 4 AND ONE MONOSACCHARIDE
ON RESIDUE 6. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000205 | | Name: | DESVANCOSAMINYL VANCOMYCIN | | Formula: | C59 H62 Cl2 N8 O22 | | Description: | DESVANCOSAMINYL VANCOMYCIN IS AN INTERMIDIATE IN VANCOMYCIN BIOSYNTHESIS. IT IS TRICYCLIC GLYCOPEPTIDE, GLYCOSYLATED
BY D-GLUCOSE (RESIDUE 8) ON RESIDUE 4. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000206 | | Name: | VANCOMYCIN AGLYCON | | Formula: | C53 H52 Cl2 N8 O17 | | Description: | VANCOMYCIN AGLYCON IS THE NONSUGAR COMPONENT OF VANCOMYCIN, CONSISTING OF THE TRICYCLIC HEPTAPEPTIDE ONLY. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000207 | | Name: | Decaplanin | | Formula: | C72 H86 Cl N9 O28 | | Description: | DECAPLANIN IS A TRICYCLIC GLYCOPEPTIDE. THE SCAFFOLD IS A HEPTAPEPTIDE WITH THE CONFIGURATION D-D-L-D-D-L-L,
GLYCOSYLATED | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000209 | | Name: | Teicoplanin A2-2 beta-D-Glucopyranuronic acid | | Formula: | C88 H97 Cl2 N9 O33 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000210 | | Name: | Teicoplanin Aglycone | | Formula: | C58 H45 Cl2 N7 O18 | | Description: | TEICOPLANIN AGLYCON IS THE NONSUGAR COMPONENT OF
TEICOPLANIN, CONSISTING OF THE TETRACYCLIC
HEPTAPEPTIDE ONLY. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000211 | | Name: | A40926 | | Formula: | C88 H95 Cl2 N9 O34 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000216 | | Name: | LEUPEPTIN | | Formula: | C20 H41 N6 O5 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000217 | | Name: | Daptomycin | | Formula: | C72 H101 N17 O26 | | Description: |
DAPTOMYCIN IS AN ACIDIC CYCLIC LIPOPEPTIDE.
THE SCAFFOLD IS MADE OF TWO PARTS:
(1) THREE RESIDUES N-TERM EXOCYCLIC PART
(2) A DECAPEPTIDE LACTONE RING DERIVED FROM
CYCLISATION OF THR3 SIDE CHAIN ONTO THE C-TER
CARBOXYL GROUP
THE N-DECANOYL FATTY ACID IS LINKED TO THE
MAIN BODY OF THE MOLECULE VIA N-TERM ACYLATION. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000219 | | Name: | GRAMICIDIN S | | Formula: | C60 H92 N12 O10 | | Description: | GRAMICIDIN S IS A DECAPEPTIDE,
RESIDUES 1 AND 10 FORM A PEPTIDE BOND
RESULTING IN CYCLIZATION. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000220 | | Name: | FEGLYMYCIN | | Formula: | C95 H97 N13 O30 | | Description: | FEGLYMYCIN IS A LINEAR HELICAL TRIDECAMER PEPTIDE | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000221 | | Name: | Nosiheptide | | Formula: | C51 H46 N13 O11 S6 | | Description: | NOSIHEPTIDE IS A HETROCYCLIC THIOPEPTIDE, CONSISTING OF FIVE THIAZOLES AND ONE 3-HYDROXYPYRIDINE RINGS. A MODIFIED
INDOLE RING NO1(14) IS LINKED VIA THE SIDE CHAINS OF 3-HYDROXY 3GL(6) AND CYS(8). THE OBSERVED C-TERMINAL AMINO GROUP
NH2(13) IS LIKELY TO BE A POST-TRANSLATIONAL DECARBOXYLATED REMNANT OF A SER C-TERMINAL RESIDUE | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000222 | | Name: | RAMOPLANIN A2 | | Formula: | C119 H154 Cl N21 O40 | | Description: | RAMOPLANIN A2 IS A CYCLIC HEPTADECAMER
LIPOGLYCODEPSIPEPTIDE.
THE SCAFFOLD IS A HEPTA CYCLIC PEPTIDE
GLYCOSYLATED BY ONE DISACCHARIDE AND A FATTY ACID
AT THE N-TERM. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000223 | | Name: | THIOSTREPTON | | Formula: | C72 H84 N19 O18 S5 | | Description: | Thiostrepton is a hetrocyclic thiopeptide belonging to the
thiocillin family, consisting of four thiazole, one thiozoline and one
piperideine rings. A modified quinoline linked to main-chain residue 1
and side-chain of residue 12. Post translational maturation of
thiazole and oxazole containing antibiotics involves the enzymic
condensation of a Cys or Ser with the alpha-carbonyl of the preceding
amino acid to form a thioether or ether bond, then dehydration to form
a double bond with the alpha-amino nitrogen. Thiazoline or oxazoline
ring are dehydrogenated to form thiazole or oxazole rings. the
pyridinyl involves the cross-linking of a Ser and a Cys-Ser pair
usually separated by 7 or 8 residues along the peptide chain. The Ser
residues are dehydrated to didehydroalanines, then bonded between
their beta carbons. The alpha carbonyl of the Cys condenses with alpha
carbon of the first Ser to form a pyridinyl ring. The ring may be
mutiply dehydrogenated to form a pyridine ring with loss of the amino
nitrogen of the first Ser. The amidation of Ser-17 probably does not
occur by the same mechanism, oxidative cleavage of glycine, as in
eukaryotes. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000225 | | Name: | GE2270a | | Formula: | C56 H58 N15 O10 S6 | | Description: | GEA2270A IS A THIOPEPTIDE CONSISTING OF ONE
PYRIDINE, ONE OXAZOLE AND FIVE THIAZOLE RINGS.
THE OBSERVED C-TERMINAL AMINO GROUP NH2(15) IS
LIKELY TO BE A POST-TRANSLATIONAL DECARBOXYLATED
REMNANT OF A SER C-TERMINAL RESIDUE. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000226 | | Name: | Viomycin | | Formula: | C25 H43 N13 O10 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000227 | | Name: | VIRGINIAMYCIN S1 | | Formula: | C43 H49 N7 O10 | | Description: | VIRGINIAMYCIN S1 IS A CYLIC HEPTAPEPTIDE. THE RING IS GENERATED BY LINKING RESIDUE 2 SIDE-CHAIN AND RESIDUE 7
MAIN-CHAIN. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000228 | | Name: | JG-365 | | Formula: | C42 H68 N8 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000231 | | Name: | N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-1-(carboxymethyl)-2-oxo-5-phenylpentyl]-L-valinamide | | Formula: | C29 H40 N4 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000233 | | Name: | N-acetyl-3-cyclohexyl-L-alanyl-N~5~-[amino(iminio)methyl]-L-ornithyl-L-alanyl-L-methionyl-S-[(acetylamino)methyl]-L-
cysteinyl-L-seryl-L-leucinamide | | Formula: | C40 H73 N12 O10 S2 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000235 | | Name: | N-acetyl-L-leucyl-L-alanyl-N-[(1R,2R)-2-hydroxy-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl]-L-alaninamide | | Formula: | C22 H39 N5 O6 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000236 | | Name: | N-acetyl-L-alanyl-N-{(1S)-3,3-difluoro-1-(1-methylethyl)-2,4-dioxo-4-[(2-phenylethyl)amino]butyl}-L-prolinamide | | Formula: | C25 H37 F2 N4 O5 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000238 | | Name: | Ac-Asp-Glu-Val-Asp-CMK | | Formula: | C21 H31 Cl N4 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000239 | | Name: | N-acetyl-L-alpha-aspartyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-L-alaninamide | | Formula: | C19 H29 F N4 O9 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
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