 | | PRD_000187 | | Name: | SCYPTOLIN A | | Formula: | C45 H71 Cl N8 O14 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000194 | | Name: | ACTAGARDINE | | Formula: | C81 H124 N20 O23 S4 | | Description: | ACTAGARDINE IS A TRICYCLIC PEPTIDE. POST TRANSLATIONAL MATURATION
OF LANTIBIOTICS INVOLVES THE ENZYMIC CONVERSION OF THR AND SER INTO
DEHYDRATED AMINO ACIDS AND THE FORMATION OF THIOETHER BONDS WITH
CYSTEINE. THE THIOETHER BONDS WITH CYSTEINE RESULT IN THREE
RING STRUCTURES. THIS IS FOLLOWED BY MEMBRANE TRANSLOCATION AND
CLEAVAGE OF THE MODIFIED PRECURSOR. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000196 | | Name: | EPILANCIN 15X | | Formula: | C145 H241 N41 O33 S3 | | Description: | Epilancin 15X is a tricyclic peptide. thioether bonds with cysteine
result in three rings along the peptide chain. Post Translational
maturation of lantibiotics involves the enzymic conversion of Thr and
Ser into dehydrated amino acids and the formation of thioether bonds
with cysteine. This is followed by membrane translocation and
cleavage of the modified precursor. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000199 | | Name: | Mersacidin | | Formula: | C80 H120 N20 O21 S4 | | Description: | MERSACIDIN IS A TETRACYCLIC PEPTIDE. POST TRANSLATIONAL MATURATION
OF LANTIBIOTICS INVOLVES THE ENZYMIC CONVERSION OF THR, AND SER INTO
DEHYDRATED AA AND THE FORMATION OF THIOETHER BONDS WITH CYSTEINE. THE
CARBOXY-TERMINAL BETA-METHYLLANTHIONINE UNDERGOES
DECARBOXYLATION. THIOETHER BONDS WITH CYSTEINE RESULT IN FOUR
RINGS. THIS IS FOLLOWED BY MEMBRANE TRANSLOCATION AND CLEAVAGE OF THE
MODIFIED PRECURSOR. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000200 | | Name: | Nisin A | | Formula: | C141 H233 N41 O38 S7 | | Description: | Nisin Z is a heptacyclic peptide. Post Translational maturation of
lantibiotics involves the enzymic conversion of Thr, and Ser into
dehydrated AA and the formation of thioether bonds with cysteine.
Thioether bonds with cysteine result in five cyclic structures along
the peptide chain. This is followed by membrane translocation and
cleavage of the modified precursor. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000217 | | Name: | Daptomycin | | Formula: | C72 H101 N17 O26 | | Description: |
DAPTOMYCIN IS AN ACIDIC CYCLIC LIPOPEPTIDE.
THE SCAFFOLD IS MADE OF TWO PARTS:
(1) THREE RESIDUES N-TERM EXOCYCLIC PART
(2) A DECAPEPTIDE LACTONE RING DERIVED FROM
CYCLISATION OF THR3 SIDE CHAIN ONTO THE C-TER
CARBOXYL GROUP
THE N-DECANOYL FATTY ACID IS LINKED TO THE
MAIN BODY OF THE MOLECULE VIA N-TERM ACYLATION. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000220 | | Name: | FEGLYMYCIN | | Formula: | C95 H97 N13 O30 | | Description: | FEGLYMYCIN IS A LINEAR HELICAL TRIDECAMER PEPTIDE | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000228 | | Name: | JG-365 | | Formula: | C42 H68 N8 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000232 | | Name: | N-[(2S)-2-benzyl-3-sulfanylpropanoyl]-L-alanylglycinamide | | Formula: | C15 H21 N3 O3 S | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000233 | | Name: | N-acetyl-3-cyclohexyl-L-alanyl-N~5~-[amino(iminio)methyl]-L-ornithyl-L-alanyl-L-methionyl-S-[(acetylamino)methyl]-L-
cysteinyl-L-seryl-L-leucinamide | | Formula: | C40 H73 N12 O10 S2 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000235 | | Name: | N-acetyl-L-leucyl-L-alanyl-N-[(1R,2R)-2-hydroxy-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl]-L-alaninamide | | Formula: | C22 H39 N5 O6 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000236 | | Name: | N-acetyl-L-alanyl-N-{(1S)-3,3-difluoro-1-(1-methylethyl)-2,4-dioxo-4-[(2-phenylethyl)amino]butyl}-L-prolinamide | | Formula: | C25 H37 F2 N4 O5 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000239 | | Name: | N-acetyl-L-alpha-aspartyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-L-alaninamide | | Formula: | C19 H29 F N4 O9 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000240 | | Name: | N-acetyl-L-isoleucyl-L-prolyl-L-Phenylalaninal | | Formula: | C22 H33 N3 O4 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000241 | | Name: | N-acetyl-L-leucyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-aspartic aldehyde | | Formula: | C24 H39 N5 O13 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000242 | | Name: | N-acetyl-L-leucyl-L-phenylalanyl-N-[(1S,2R)-1-(2-carboxyethyl)-3-fluoro-2-hydroxypropyl]-L-phenylalaninamide | | Formula: | C32 H43 F N4 O7 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000243 | | Name: | N-acetyl-3-(naphthalen-1-yl)-L-alanyl-L-valyl-L-leucyl-L-alanyl-L-alpha-glutamyl-3-naphthalen-1-yl-
L-alaninamide | | Formula: | C47 H59 N7 O9 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000245 | | Name: | 1-acetyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-N-(1-methylethyl)glycyl-L-prolyl-N~5~-[amino(iminio)methyl]-L-ornithyl-
N~5~-[amino(iminio)methyl]-L-ornithine | | Formula: | C44 H76 N14 O10 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000252 | | Name: | Ac-Tyr-Val-Ala-Asp-Aldehyde | | Formula: | C23 H32 N4 O8 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000257 | | Name: | N-{(2S)-2-[(N-acetyl-4-carbamimidoyl-L-phenylalanyl)amino]-2-cyclohexylacetyl}-3-(1-methylpyridinium-3-yl)-
L-alanyl-D-leucyl-L-prolinamide | | Formula: | C40 H58 N9 O6 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000259 | | Name: | N-acetyl-L-tryptophyl-L-alpha-glutamyl-N-[(1R)-2-carboxy-1-formylethyl]-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide | | Formula: | C28 H36 N7 O9 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000265 | | Name: | (2S)-2-[[(3S,4S)-5-cyclohexyl-4-[[(4S,5S)-5-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxidanyl-6-phenyl-hexanoyl]amino]
-3-oxidanyl-pentanoyl]amino]-4-methyl-pentanoic acid | | Formula: | C34 H55 N3 O8 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000266 | | Formula: | C52 H81 N11 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000267 | | Name: | H-261 Oligopeptide | | Formula: | C55 H84 N13 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000268 | | Name: | L-364,099 | | Formula: | C54 H77 N11 O11 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
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