6XJA

Streptococcus Pneumoniae IgA1 Protease with IgA1 substrate

Summary for 6XJA

Entry DOI	10.2210/pdb6xja/pdb
EMDB information	22204
Descriptor	Immunoglobulin A1 protease, Immunoglobulin heavy constant alpha 1, Immunoglobulin alpha-1 light chain, ... (4 entities in total)
Functional Keywords	iga1, complex, protease, metalloprotease, immune system
Biological source	Streptococcus pneumoniae (strain ATCC BAA-255 / R6) More
Total number of polymer chains	5
Total formula weight	235580.34
Authors	Eisenmesser, E.Z.,Zheng, H. (deposition date: 2020-06-23, release date: 2021-01-20)
Primary citation	Wang, Z.,Rahkola, J.,Redzic, J.S.,Chi, Y.C.,Tran, N.,Holyoak, T.,Zheng, H.,Janoff, E.,Eisenmesser, E. Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. Nat Commun, 11:6063-6063, 2020 Cited by PubMed: 33247098 DOI: 10.1038/s41467-020-19887-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation