6LU7
The crystal structure of COVID-19 main protease in complex with an inhibitor N3
Summary for 6LU7
Entry DOI | 10.2210/pdb6lu7/pdb |
Related PRD ID | PRD_002214 |
Descriptor | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE (3 entities in total) |
Functional Keywords | protease, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 34506.34 |
Authors | |
Primary citation | Jin, Z.,Du, X.,Xu, Y.,Deng, Y.,Liu, M.,Zhao, Y.,Zhang, B.,Li, X.,Zhang, L.,Peng, C.,Duan, Y.,Yu, J.,Wang, L.,Yang, K.,Liu, F.,Jiang, R.,Yang, X.,You, T.,Liu, X.,Yang, X.,Bai, F.,Liu, H.,Liu, X.,Guddat, L.W.,Xu, W.,Xiao, G.,Qin, C.,Shi, Z.,Jiang, H.,Rao, Z.,Yang, H. Structure of Mprofrom SARS-CoV-2 and discovery of its inhibitors. Nature, 582:289-293, 2020 Cited by PubMed: 32272481DOI: 10.1038/s41586-020-2223-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
Download full validation report