6GG3
Crystal structure of M2 PYK in complex with Alanine.
Summary for 6GG3
| Entry DOI | 10.2210/pdb6gg3/pdb |
| Descriptor | Pyruvate kinase PKM, PHOSPHATE ION, ALANINE (3 entities in total) |
| Functional Keywords | glycolysis, pyruvate kinase activity, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 12 |
| Total formula weight | 724378.68 |
| Authors | McNae, I.W.,Yuan, M.,Walkinshaw, M.D. (deposition date: 2018-05-02, release date: 2019-09-04, Last modification date: 2024-01-17) |
| Primary citation | Yuan, M.,McNae, I.W.,Chen, Y.,Blackburn, E.A.,Wear, M.A.,Michels, P.A.M.,Fothergill-Gilmore, L.A.,Hupp, T.,Walkinshaw, M.D. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor. Biochem.J., 475:1821-1837, 2018 Cited by PubMed: 29748232DOI: 10.1042/BCJ20180171 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.72 Å) |
Structure validation
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