5CFU
Crystal Structure of ANT(2")-Ia in complex with adenylyl-2"-tobramycin
Summary for 5CFU
| Entry DOI | 10.2210/pdb5cfu/pdb |
| Related | 4XJE 5CFS 5CFT |
| Descriptor | Aminoglycoside Nucleotidyltransferase (2")-Ia, MANGANESE (II) ION, adenylyl-2"-tobramycin, ... (6 entities in total) |
| Functional Keywords | antibiotic resistance, nucleotidyltransferase, ampcpp, tobramycin, modified aminoglycoside, rossmann fold, transferase-antibiotic complex, transferase/antibiotic |
| Biological source | Pseudomonas aeruginosa |
| Total number of polymer chains | 1 |
| Total formula weight | 22493.40 |
| Authors | Rodionov, D.,Bassenden, A.V.,Berghuis, A.M. (deposition date: 2015-07-08, release date: 2016-07-20, Last modification date: 2023-09-27) |
| Primary citation | Bassenden, A.V.,Park, J.,Rodionov, D.,Berghuis, A.M. Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study. Acs Chem.Biol., 2020 Cited by PubMed: 32100995DOI: 10.1021/acschembio.9b00904 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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