4LP5
Crystal structure of the full-length human RAGE extracellular domain (VC1C2 fragment)
Summary for 4LP5
| Entry DOI | 10.2210/pdb4lp5/pdb |
| Related | 4LP4 |
| Descriptor | Advanced glycosylation end product-specific receptor (1 entity in total) |
| Functional Keywords | immunoglobulin fold, pattern recognition receptor, signaling receptor, membrane, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 10: Cell membrane ; Single-pass type I membrane protein : Q15109 |
| Total number of polymer chains | 2 |
| Total formula weight | 65360.59 |
| Authors | Yatime, L.,Andersen, G.R. (deposition date: 2013-07-15, release date: 2013-10-16, Last modification date: 2023-09-20) |
| Primary citation | Yatime, L.,Andersen, G.R. Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products. Febs J., 280:6556-6568, 2013 Cited by PubMed: 24119142DOI: 10.1111/febs.12556 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.8 Å) |
Structure validation
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