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4ERS

A Molecular Basis for Negative Regulation of the Glucagon Receptor

Summary for 4ERS
Entry DOI10.2210/pdb4ers/pdb
DescriptorFab light chain, Fab heavy chain, Glucagon receptor, ... (5 entities in total)
Functional Keywordsglucagon receptor, class-b gpcr, fab, glycosylation, extra-cellular, immune system
Biological sourceHomo sapiens
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Cellular locationCell membrane; Multi-pass membrane protein: P47871
Total number of polymer chains3
Total formula weight60104.22
Authors
Murray, J.M.,Koth, C.M.,Mukund, S. (deposition date: 2012-04-20, release date: 2012-08-29, Last modification date: 2020-07-29)
Primary citationKoth, C.M.,Murray, J.M.,Mukund, S.,Madjidi, A.,Minn, A.,Clarke, H.J.,Wong, T.,Chiang, V.,Luis, E.,Estevez, A.,Rondon, J.,Zhang, Y.,Hotzel, I.,Allan, B.B.
Molecular basis for negative regulation of the glucagon receptor.
Proc.Natl.Acad.Sci.USA, 109:14393-14398, 2012
Cited by
PubMed: 22908259
DOI: 10.1073/pnas.1206734109
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.637 Å)
Structure validation

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