4AWB
Crystal structure of active legumain in complex with AAN-CMK
Summary for 4AWB
| Entry DOI | 10.2210/pdb4awb/pdb |
| Related | 4AW9 4AWA 4FGU |
| Related PRD ID | PRD_002087 |
| Descriptor | LEGUMAIN, Z-ALA-ALA-AZAASN-CHLOROMETHYLKETONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | hydrolase-inhibitor complex, hydrolase, cysteine protease, lysosomal, aep, substrate specificity, mhcii, antigen processing, cancer, hydrolase/inhibitor |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Total number of polymer chains | 4 |
| Total formula weight | 67788.76 |
| Authors | Dall, E.,Brandstetter, H. (deposition date: 2012-06-01, release date: 2013-06-26, Last modification date: 2023-12-20) |
| Primary citation | Dall, E.,Brandstetter, H. Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110:10940-, 2013 Cited by PubMed: 23776206DOI: 10.1073/PNAS.1300686110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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