3OS1
PFV target capture complex (TCC) at 2.97 A resolution
Summary for 3OS1
Entry DOI | 10.2210/pdb3os1/pdb |
Related | 3L2R 3OS0 3OS2 |
Descriptor | Integrase, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*(2DA))-3'), ... (7 entities in total) |
Functional Keywords | protein-dna complex, tetramer, dna integration, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, zinc binding, hhcc motif, viral protein, recombination, recombination-dna complex, recombination/dna |
Biological source | Human spumaretrovirus More |
Cellular location | Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350 |
Total number of polymer chains | 5 |
Total formula weight | 109364.57 |
Authors | Maertens, G.N.,Hare, S.,Cherepanov, P. (deposition date: 2010-09-08, release date: 2010-11-17, Last modification date: 2023-11-01) |
Primary citation | Maertens, G.N.,Hare, S.,Cherepanov, P. The mechanism of retroviral integration from X-ray structures of its key intermediates Nature, 468:326-329, 2010 Cited by PubMed: 21068843DOI: 10.1038/nature09517 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.97 Å) |
Structure validation
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