2XOW
Structure of GlpG in complex with a mechanism-based isocoumarin inhibitor
Summary for 2XOW
| Entry DOI | 10.2210/pdb2xow/pdb |
| Related | 2IC8 2IRV 2XOV |
| Descriptor | RHOMBOID PROTEASE GLPG, 5-AMINO-2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID, nonyl beta-D-glucopyranoside, ... (4 entities in total) |
| Functional Keywords | hydrolase, membrane protein, intramembrane protease |
| Biological source | ESCHERICHIA COLI |
| Total number of polymer chains | 1 |
| Total formula weight | 25325.54 |
| Authors | Vinothkumar, K.R.,Strisovsky, K.,Andreeva, A.,Christova, Y.,Verhelst, S.,Freeman, M. (deposition date: 2010-08-24, release date: 2010-10-13, Last modification date: 2023-12-20) |
| Primary citation | Vinothkumar, K.R.,Strisovsky, K.,Andreeva, A.,Christova, Y.,Verhelst, S.,Freeman, M. The Structural Basis for Catalysis and Substrate Specificity of a Rhomboid Protease Embo J., 29:3797-, 2010 Cited by PubMed: 20890268DOI: 10.1038/EMBOJ.2010.243 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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