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2K9J

Integrin alphaIIb-beta3 transmembrane complex

Summary for 2K9J
Entry DOI10.2210/pdb2k9j/pdb
Related2RMZ 2k1a
NMR InformationBMRB: 16497
DescriptorIntegrin alpha-IIb light chain, Integrin beta-3 (2 entities in total)
Functional Keywordsintegrin, transmembrane complex, cell adhesion, cleavage on pair of basic residues, disease mutation, glycoprotein, pyrrolidone carboxylic acid, receptor, host-virus interaction, phosphoprotein, membrane protein
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein: P08514 P05106
Total number of polymer chains2
Total formula weight9464.62
Authors
Lau, T.,Kim, C.,Ginsberg, M.H.,Ulmer, T.S. (deposition date: 2008-10-15, release date: 2009-03-24, Last modification date: 2021-10-20)
Primary citationLau, T.L.,Kim, C.,Ginsberg, M.H.,Ulmer, T.S.
The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
Embo J., 28:1351-1361, 2009
Cited by
PubMed: 19279667
DOI: 10.1038/emboj.2009.63
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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