2CAG

CATALASE COMPOUND II

Summary for 2CAG

Entry DOI	10.2210/pdb2cag/pdb
Descriptor	CATALASE COMPOUND II, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	oxidoreductase (h2o2 acceptor), peroxidase, iron, heme, hydrogen peroxide, nadp
Biological source	Proteus mirabilis
Cellular location	Cytoplasm: P42321
Total number of polymer chains	1
Total formula weight	56342.83
Authors	Gouet, P.,Jouve, H.M.,Hajdu, J. (deposition date: 1996-06-12, release date: 1996-12-07, Last modification date: 2024-10-23)
Primary citation	Gouet, P.,Jouve, H.M.,Williams, P.A.,Andersson, I.,Andreoletti, P.,Nussaume, L.,Hajdu, J. Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy. Nat.Struct.Biol., 3:951-956, 1996 Cited by PubMed Abstract: Various enzymes use semi-stable ferryl intermediates and free radicals during their catalytic cycle, amongst them haem catalases. Structures for two transient intermediates (compounds I and II) of the NADPH-dependent catalase from Proteus mirabilis (PMC) have been determined by time-resolved X-ray crystallography and single crystal microspectrophotometry. The results show the formation and transformation of the ferryl group in the haem, and the unexpected binding of an anion during this reaction at a site distant from the haem. PubMed: 8901874 DOI: 10.1038/nsb1196-951 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation