1CKT
CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX
Summary for 1CKT
Entry DOI | 10.2210/pdb1ckt/pdb |
Descriptor | DNA (5'-D(*CP*CP*(5IU)P*CP*TP*CP*TP*GP*GP*AP*CP*CP*TP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*GP*TP*CP*CP*AP*GP*AP*GP*AP*GP*G)-3'), HIGH MOBILITY GROUP 1 PROTEIN, ... (5 entities in total) |
Functional Keywords | high-mobility group domain, bent dna, protein-drug-dna complex, gene regulation-dna complex, gene regulation/dna |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Nucleus: P63159 |
Total number of polymer chains | 3 |
Total formula weight | 18708.06 |
Authors | Ohndorf, U.-M.,Rould, M.A.,Pabo, C.O.,Lippard, S.J. (deposition date: 1999-04-23, release date: 1999-06-30, Last modification date: 2023-12-27) |
Primary citation | Ohndorf, U.M.,Rould, M.A.,He, Q.,Pabo, C.O.,Lippard, S.J. Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. Nature, 399:708-712, 1999 Cited by PubMed: 10385126DOI: 10.1038/21460 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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