1AX8

Human obesity protein, leptin

Summary for 1AX8

Entry DOI	10.2210/pdb1ax8/pdb
Descriptor	OBESITY PROTEIN (2 entities in total)
Functional Keywords	helical cytokine, hematopoietic factor, diabetes, obesity, cytokine
Biological source	Homo sapiens (human)
Cellular location	Secreted: P41159
Total number of polymer chains	1
Total formula weight	15984.30
Authors	Zhang, F.,Beals, J.M.,Briggs, S.L.,Clawson, D.K.,Wery, J.-P.,Schevitz, R.W. (deposition date: 1997-10-31, release date: 1998-11-25, Last modification date: 2012-05-09)
Primary citation	Zhang, F.,Basinski, M.B.,Beals, J.M.,Briggs, S.L.,Churgay, L.M.,Clawson, D.K.,DiMarchi, R.D.,Furman, T.C.,Hale, J.E.,Hsiung, H.M.,Schoner, B.E.,Smith, D.P.,Zhang, X.Y.,Wery, J.P.,Schevitz, R.W. Crystal structure of the obese protein leptin-E100. Nature, 387:206-209, 1997 Cited by PubMed: 9144295 DOI: 10.1038/387206a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation