9YD2

Ternary complex of DNA polymerase I from Bacillus stearothermophilus, large fragment, bound to DNA containing a thymine dimer and dATP

Summary for 9YD2

• Entry DOI: 10.2210/pdb9yd2/pdb
• Descriptor: DNA polymerase I, DNA (5'-D(*CP*AP*AP*GP*GP*AP*CP*AP*GP*TP*(DDG))-3'), DNA (5'-D(*AP*(TTD)P*CP*AP*CP*TP*GP*TP*CP*CP*TP*TP*G)-3'), ... (7 entities in total)
• Functional Keywords: polymerase, complex, replication
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 3
• Total formula weight: 75309.74

Authors

Wu, E.Y.,Walsh, A.R. (deposition date: 2025-09-20, release date: 2026-06-24)

• Primary citation: Walsh, A.R.,Beese, L.S.,Wu, E.Y.; Structural basis for blockage of DNA synthesis by a thymine dimer lesion in a high-fidelity DNA polymerase; Biochemistry, 2026; DOI: 10.1021/acs.biochem.5c00781

Experimental method

X-RAY DIFFRACTION (2.249 Å)