9X7C

Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Mivebresib ABBV-075

9X7C の概要

• エントリーDOI: 10.2210/pdb9x7c/pdb
• 分子名称: Bromodomain-containing protein 2, N-[4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide (3 entities in total)
• 機能のキーワード: brd2, cancer ligand bound, inhbitor, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 40096.57

構造登録者

Jwala, N.,Chandrasekhar, A.,NarasimhaRao, K. (登録日: 2025-10-16, 公開日: 2025-10-29)

• 主引用文献: Jwala, N.,Chandrasekhar, A.,NarasimhaRao, K.; Crystal Structure of BRD2 BD1 domain in complex with small molecule inhibitor Mivebresib ABBV-075; To Be Published,

実験手法

X-RAY DIFFRACTION (2.3 Å)