9VM2

Structure of DOCK6-Cdc42 complex protomer

Summary for 9VM2

• Entry DOI: 10.2210/pdb9vm2/pdb
• EMDB information: 65174
• Descriptor: Dedicator of cytokinesis protein 6, Cell division control protein 42 homolog (2 entities in total)
• Functional Keywords: dock, gef, rho, small gtpase, rac, cdc42, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 251740.87

Authors

Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Yonemochi, M.,Hanada, K.,Shirouzu, M. (deposition date: 2025-06-27, release date: 2026-06-03)

• Primary citation: Kukimoto-Niino, M.,Katsura, K.,Yoshimura, K.,Ishizuka-Katsura, Y.,Miyamoto, Y.,Yonemochi, M.,Hanada, K.,Yamauchi, J.,Wong, R.W.,Shirouzu, M.; Structural basis for auto-inhibition of the Rac1/Cdc42 guanine nucleotide exchange factor DOCK6 by oligomer formation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.94 Å)