9ULE

Crystal structure of CYP105A1 R84A complexed with diclofenac (DIF) at room temperature

Summary for 9ULE

• Entry DOI: 10.2210/pdb9ule/pdb
• Related: 9JI6
• Descriptor: Vitamin D3 dihydroxylase, PROTOPORPHYRIN IX CONTAINING FE, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ... (4 entities in total)
• Functional Keywords: p450, cyp105a1, nonsteroidal anti-inflammatory drugs, diclofenac, flufenamic acid, r84a, oxidoreductase
• Biological source: Streptomyces griseolus
• Total number of polymer chains: 1
• Total formula weight: 45904.38

Authors

Mikami, B.,Takita, T.,Yoneda, S.,Yasuda, K.,Sakaki, T.,Yasukawa, K. (deposition date: 2025-04-19, release date: 2026-04-22)

• Primary citation: Takita, T.,Yoneda, S.,Yasuda, K.,Mizutani, K.,Yasukawa, K.,Mikami, B.,Sakaki, T.; Complex formation of Streptomyces griseolus CYP105A1 with statins by room-temperature crystal data collection; to be published,

Experimental method

X-RAY DIFFRACTION (1.86 Å)