9RFB

Crystal Structure of Human Rac1 in Complex with the Scaffold Protein POSH (residues 321-348)

Summary for 9RFB

• Entry DOI: 10.2210/pdb9rfb/pdb
• Descriptor: Ras-related C3 botulinum toxin substrate 1, E3 ubiquitin-protein ligase SH3RF1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (7 entities in total)
• Functional Keywords: gtpase gtp/gdp-binding nucleotide binding, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 47457.59

Authors

Kjaer, L.F.,Ielasi, F.S.,Palencia, A.,Jensen, M.R. (deposition date: 2025-06-04, release date: 2025-12-03)

• Primary citation: Kjaer, L.F.,Ielasi, F.S.,Winbolt, T.,Delaforge, E.,Tengo, M.,Bessa, L.M.,Marino-Perez, L.,Boeri-Erba, E.,Bouvignies, G.,Palencia, A.,Jensen, M.R.; Hierarchical Folding-Upon-Binding of an Intrinsically Disordered Protein; Nat Commun, 2025; DOI: 10.1038/s41467-025-66420-5

Experimental method

X-RAY DIFFRACTION (1.854 Å)