9RF5

M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography: ELF8

Summary for 9RF5

• Entry DOI: 10.2210/pdb9rf5/pdb
• Descriptor: Monoacylglycerol lipase, [(3~{R})-3-oxidanylpyrrolidin-1-yl]-[4-[2-[3-(trifluoromethyloxy)phenyl]-1,3-oxazol-5-yl]phenyl]methanone, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (7 entities in total)
• Functional Keywords: rv0183, inhibitor, monoacylglycerol lipase, hydrolase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 1
• Total formula weight: 34472.95

Authors

Riegler-Berket, L.,Goedl, L.,Oberer, M.,Polidori, N. (deposition date: 2025-06-04, release date: 2025-08-13)

• Primary citation: Riegler-Berket, L.,Goedl, L.,Oberer, M.,Polidori, N.; M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)