9RCV

Structure of the Human Peptide-Loading Complex Arrested by HCMV US6

Summary for 9RCV

• Entry DOI: 10.2210/pdb9rcv/pdb
• EMDB information: 53923
• Descriptor: Antigen peptide transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... (12 entities in total)
• Functional Keywords: antigen processing, adaptive immunity, cryo-em, er chaperones, mhc class i, transporter associated with antigen processing, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 382497.08

Authors

Stolz, M.,Susac, L.,Trowitzsch, S.,Tampe, R. (deposition date: 2025-05-29, release date: 2025-12-03)

• Primary citation: Stolz, M.,Susac, L.,Trowitzsch, S.,Tampe, R.; US6 hijacks peptide-loading complex by trapping transporter-chaperone dynamics; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.7 Å)