9RBD

Cryo-EM structure of ANP amyloids from left atrial appendage of atrial fibrillation patient - polymorph A

Summary for 9RBD

• Entry DOI: 10.2210/pdb9rbd/pdb
• EMDB information: 53891
• Descriptor: Natriuretic peptides A (1 entity in total)
• Functional Keywords: amyloid, cardiac amyloidosis, in vivo, aggregation, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 20
• Total formula weight: 51457.64

Authors

Broggini, L.,Chaves-Sanjuan, A.,Ricagno, S. (deposition date: 2025-05-22, release date: 2025-08-27)

• Primary citation: Broggini, L.,Piccoli, M.,Chaves-Sanjuan, A.,Bonnet, D.M.,Cirillo, F.,Visentin, C.,Sonzini, F.,Signorelli, P.,Lavota, I.,Milazzo, M.,Nonnis, S.,Menicanti, L.,Ciconte, G.,Pappone, C.,Anastasia, L.,Ricagno, S.; Structural characterization of atrial natriuretic peptide amyloid fibrils from patients with atrial fibrillation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.96 Å)